{"id":"W2123472930","doi":"10.1261/rna.052225.115","title":"eIF4AII is dispensable for miRNA-mediated gene silencing","year":2015,"lang":"en","type":"article","venue":"RNA","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Lady Davis Institute for Medical Research; Canadian Institutes of Health Research; Friedrich Miescher Institute for Biomedical Research; McGill University; Dana-Farber/Harvard Cancer Center","keywords":"Biology; Gene silencing; microRNA; RNA interference; Psychological repression; Untranslated region; CRISPR; Genetics; Translation (biology); Gene expression; Regulation of gene expression; Gene; Three prime untranslated region; Argonaute; Cell biology; RNA; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002601438,0.0005451693,0.0005129006,0.0004048619,0.000253725,0.0005097949,0.0005098495,0.0004460455,0.001680918],"category_scores_gemma":[0.0003731023,0.0002900439,0.000372917,0.0002375739,0.0003910603,0.0002838084,0.0003464636,0.000739947,0.0009814107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003357679,"about_ca_system_score_gemma":0.0003819251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004649287,"about_ca_topic_score_gemma":0.0005652177,"domain_scores_codex":[0.9996473,0.00004625485,0.0000581868,0.00007214877,0.0001238732,0.00005236255],"domain_scores_gemma":[0.9994346,0.000168393,0.0001466558,0.00008699367,0.00004082618,0.0001224438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000459498,0.00001119009,0.0001075029,0.00001967326,0.000003897406,0.00008271998,0.000004904314,0.00004255998,0.9988067,0.0001180999,0.00003288191,0.0007239531],"study_design_scores_gemma":[0.00001532953,0.00006662863,0.002346082,0.00000578754,0.00001267791,0.0004634456,0.00001322288,0.001288509,0.9916956,0.00009576112,0.003988875,0.000008132184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9754543,0.001912224,0.01556416,0.0002617942,0.0001507415,0.000047284,0.001700601,0.0006385968,0.00427044],"genre_scores_gemma":[0.9893835,0.000531306,0.004537278,0.00006805376,0.00001725253,0.00004158313,0.001353913,0.0001449977,0.003922046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001680918,"threshold_uncertainty_score":0.005623221,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01895255021518163,"score_gpt":0.3066753999127982,"score_spread":0.2877228496976166,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}