{"id":"W2123472930","doi":"10.1261/rna.052225.115","title":"eIF4AII is dispensable for miRNA-mediated gene silencing","year":2015,"lang":"en","type":"article","venue":"RNA","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Lady Davis Institute for Medical Research; Canadian Institutes of Health Research; Friedrich Miescher Institute for Biomedical Research; McGill University; Dana-Farber/Harvard Cancer Center","keywords":"Biology; Gene silencing; microRNA; RNA interference; Psychological repression; Untranslated region; CRISPR; Genetics; Translation (biology); Gene expression; Regulation of gene expression; Gene; Three prime untranslated region; Argonaute; Cell biology; RNA; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009454761,0.00009316611,0.00008572725,0.00001804991,0.00002876369,0.0000132289,0.00009754644,0.00007735297,0.00001402334],"category_scores_gemma":[0.0000691136,0.00009151871,0.00005427169,0.00004218139,0.00001284914,0.000001612182,0.00004228598,0.00003151106,0.00002502194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001079554,"about_ca_system_score_gemma":0.0000407726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001692861,"about_ca_topic_score_gemma":0.000007908907,"domain_scores_codex":[0.9994273,0.000005614594,0.0001055559,0.000188169,0.00007221629,0.0002011125],"domain_scores_gemma":[0.9995962,0.000007280408,0.0000228138,0.0002007449,0.00006113958,0.0001118012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002437703,0.00001445636,0.0002451329,0.00001357782,0.00002315541,0.000001047798,0.0001373463,0.0003252779,0.9799072,0.000006205215,0.01831883,0.0009834248],"study_design_scores_gemma":[0.0004537936,0.0001276747,0.0001939993,0.00000592209,0.00001208728,0.000005690566,0.00008289683,0.00134691,0.9360396,0.00003889047,0.06154754,0.0001449495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9662059,0.001662494,0.03031549,0.0001365237,0.00030887,0.0001554406,0.00003944418,0.00001973968,0.001156093],"genre_scores_gemma":[0.9950745,0.00007192467,0.002780598,0.0002529077,0.0003396369,0.00002033171,0.0001043895,0.00002270325,0.001332972],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04386752,"threshold_uncertainty_score":0.3732025,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01895255021518163,"score_gpt":0.3066753999127982,"score_spread":0.2877228496976166,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}