{"id":"W2123496677","doi":"10.1128/mcb.06321-11","title":"Prostate Apoptosis Response 4 (Par-4), a Novel Substrate of Caspase-3 during Apoptosis Activation","year":2011,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Canadian Institutes of Health Research","keywords":"Cleavage (geology); Apoptosis; Biology; Caspase; Cleavage stimulation factor; Molecular biology; Caspase 3; Poly ADP ribose polymerase; Caspase 7; Cell biology; Caspase 8; Caspase-9; Caspase 2; Cleavage factor; Programmed cell death; Biochemistry; Enzyme; Gene; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001814972,0.0004419652,0.0003123525,0.0003325497,0.0002867264,0.0003975558,0.0003947622,0.0004549166,0.001316054],"category_scores_gemma":[0.0002208077,0.0001661237,0.0006261965,0.0003144397,0.0002494236,0.0004214206,0.000315754,0.0008085183,0.000589452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004441258,"about_ca_system_score_gemma":0.0002402882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002692467,"about_ca_topic_score_gemma":0.0002517858,"domain_scores_codex":[0.9997233,0.00005171465,0.00001808759,0.00006329985,0.00008358768,0.00006007724],"domain_scores_gemma":[0.9998561,0.0000157705,0.00006622701,0.00001384338,0.00002384125,0.00002417377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001614672,0.00002021194,0.0006085868,0.0001071581,0.0000171854,0.0003785012,0.0000263965,0.0001189356,0.9937097,0.0002990173,0.0001412726,0.004411599],"study_design_scores_gemma":[0.00003816768,0.0003232317,0.008322126,0.00001010142,0.00004505133,0.005039671,0.00003919831,0.0009707335,0.9737244,0.0002673742,0.01119855,0.00002144546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9310259,0.0140953,0.04827992,0.0005248014,0.0001461706,0.0001668111,0.001248504,0.0006226406,0.003890033],"genre_scores_gemma":[0.9740714,0.003485138,0.01626135,0.000224378,0.00004334315,0.00007414684,0.002123316,0.00003837549,0.00367854],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001316054,"threshold_uncertainty_score":0.004402578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01251939510172679,"score_gpt":0.209450095308478,"score_spread":0.1969307002067512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}