{"id":"W2123509152","doi":"10.4049/jimmunol.1203130","title":"MMTV Superantigens Coerce an Unconventional Topology between the TCR and MHC Class II","year":2014,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Superantigen; T-cell receptor; Peptide; MHC class II; Antigen presentation; Cell biology; MHC restriction; T cell; Major histocompatibility complex; Biology; Tyrosine; Chemistry; Antigen; Topology (electrical circuits); Biochemistry; Immune system; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008321053,0.0002111545,0.00009264526,0.00009390023,0.0001130957,0.0003006487,0.0001089555,0.0001519803,0.0006924697],"category_scores_gemma":[0.00008047545,0.0001000818,0.0001223749,0.00007456483,0.0001416759,0.0001674126,0.0001823197,0.0004535137,0.0002435431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001811664,"about_ca_system_score_gemma":0.000101392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001551742,"about_ca_topic_score_gemma":0.0003051278,"domain_scores_codex":[0.9998819,0.00002262287,0.00001046191,0.00002030277,0.00003632472,0.0000283141],"domain_scores_gemma":[0.9999287,0.00001591141,0.00002112415,0.00001173408,0.000006887988,0.00001566353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001321415,0.000002978558,0.0001855064,0.000004828577,0.000001274045,0.00002024483,0.000005437019,0.0000219665,0.9994875,0.00007505687,0.000003721714,0.0001781296],"study_design_scores_gemma":[0.000004826739,0.0001743526,0.004625138,0.000003390256,0.00000791643,0.0003068616,0.00006465946,0.0009267809,0.9922799,0.00008361357,0.001520231,0.00000230091],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975995,0.0001005865,0.001688218,0.00001576301,0.000007013451,0.000006526204,0.00003614996,0.00002123882,0.00052498],"genre_scores_gemma":[0.998017,0.00008715174,0.001209059,0.0000285475,0.000004865446,0.0000050231,0.0001191116,0.00001091063,0.0005184189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006924697,"threshold_uncertainty_score":0.002316475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0143778055648045,"score_gpt":0.2370617793930208,"score_spread":0.2226839738282163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}