{"id":"W2123509518","doi":"10.1128/jb.182.9.2370-2375.2000","title":"Functional Expression in <i>Escherichia coli</i> and Membrane Topology of Porin HopE, a Member of a Large Family of Conserved Proteins in <i>Helicobacter pylori</i>","year":2000,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Helicobacter pylori-related gastroenterology studies","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Medical Research Council Canada","keywords":"Porin; Biology; Bacterial outer membrane; Transmembrane protein; Escherichia coli; Membrane protein; Peptide sequence; Colicin; Amino acid; Transmembrane domain; Membrane topology; Mutagenesis; Biochemistry; Membrane; Topology (electrical circuits); Mutation; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002619662,0.0002474874,0.0001854477,0.0001363218,0.0001268516,0.0003489775,0.0002153767,0.0002908383,0.0004219094],"category_scores_gemma":[0.0002442235,0.0001806482,0.0002599031,0.0002278646,0.0002238211,0.0002029432,0.0002762335,0.000470203,0.0002497116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004235648,"about_ca_system_score_gemma":0.0001867154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001022036,"about_ca_topic_score_gemma":0.0009438773,"domain_scores_codex":[0.9998298,0.00004677164,0.00002174799,0.00002259601,0.00004268719,0.00003642881],"domain_scores_gemma":[0.9998301,0.00004324718,0.00004706666,0.00002346286,0.00002179239,0.00003425234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001329541,0.0000397673,0.0002373546,0.00003307021,0.00000416831,0.0000428712,0.00004481429,0.0001595266,0.9985628,0.0001900952,0.00002369189,0.0005289924],"study_design_scores_gemma":[0.00002288677,0.0002971502,0.004127963,0.00001036459,0.00002033703,0.0002065315,0.0001079027,0.002580584,0.9906015,0.00004766521,0.001969583,0.000007453447],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963263,0.0001991923,0.002457834,0.00005674004,0.00001018227,0.00003387373,0.0004122586,0.00002622664,0.0004773148],"genre_scores_gemma":[0.9918493,0.0002403529,0.005321892,0.00003060906,0.000004019192,0.00003022483,0.001308488,0.00003200035,0.001183098],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001022036,"threshold_uncertainty_score":0.003073215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01849133472916992,"score_gpt":0.2556518243818631,"score_spread":0.2371604896526932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}