{"id":"W2123517618","doi":"10.1534/genetics.106.063990","title":"<i>sli-3</i> Negatively Regulates the LET-23/Epidermal Growth Factor Receptor-Mediated Vulval Induction Pathway in <i>Caenorhabditis elegans</i>","year":2006,"lang":"en","type":"article","venue":"Genetics","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institutes of Health; Breast Cancer Research Foundation; McMaster University; National Institute of General Medical Sciences; Eunice Kennedy Shriver National Institute of Child Health and Human Development; U.S. Public Health Service","keywords":"Biology; Caenorhabditis elegans; Signal transduction; Genetics; Genetic screen; Mutant; Embryonic Induction; Phenotype; Mutation; Cell biology; TOR signaling; Gene; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002533147,0.0003967218,0.0002825935,0.00008636442,0.0002098419,0.00008978184,0.0004625696,0.0003907176,0.00004020629],"category_scores_gemma":[0.0001038921,0.0003511345,0.0001284781,0.0002722382,0.0002852286,0.0000116853,0.0001729965,0.0003208662,0.00005760511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004915309,"about_ca_system_score_gemma":0.0001550786,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002460646,"about_ca_topic_score_gemma":0.0008287599,"domain_scores_codex":[0.9976009,0.0002315695,0.0005462384,0.0006348661,0.0003472769,0.0006391952],"domain_scores_gemma":[0.9988735,0.00004801259,0.0002106711,0.0005593281,0.0001987627,0.0001097644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003502804,0.0001319966,0.01173172,0.00002251923,0.00003688212,0.000006198135,0.0004271828,0.001016605,0.9762924,0.00008025598,0.00898663,0.001232524],"study_design_scores_gemma":[0.000817557,0.0002531979,0.04240088,0.00001507545,0.00001642299,0.00002774804,0.0001536169,0.0001305211,0.9017089,0.0005983881,0.05336115,0.0005165535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947639,0.001525834,0.001195653,0.0008860617,0.0006299321,0.0004108739,0.000153015,0.00004394137,0.0003907724],"genre_scores_gemma":[0.9945924,0.0005586742,0.00156702,0.0006950537,0.001184223,0.0000344486,0.0006096715,0.00008028255,0.0006782069],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07458357,"threshold_uncertainty_score":0.9998941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008250088318797998,"score_gpt":0.1989144206838963,"score_spread":0.1906643323650982,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}