{"id":"W2123517618","doi":"10.1534/genetics.106.063990","title":"<i>sli-3</i> Negatively Regulates the LET-23/Epidermal Growth Factor Receptor-Mediated Vulval Induction Pathway in <i>Caenorhabditis elegans</i>","year":2006,"lang":"en","type":"article","venue":"Genetics","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institutes of Health; Breast Cancer Research Foundation; McMaster University; National Institute of General Medical Sciences; Eunice Kennedy Shriver National Institute of Child Health and Human Development; U.S. Public Health Service","keywords":"Biology; Caenorhabditis elegans; Signal transduction; Genetics; Genetic screen; Mutant; Embryonic Induction; Phenotype; Mutation; Cell biology; TOR signaling; Gene; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006386598,0.0004237835,0.0001342746,0.0001935827,0.0002362412,0.0002639523,0.0002622476,0.0001957654,0.0008162121],"category_scores_gemma":[0.00006083445,0.0001395448,0.0002261916,0.00007421319,0.000292242,0.0001079036,0.0002189221,0.0004063741,0.0004242735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005515395,"about_ca_system_score_gemma":0.0002872674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001920997,"about_ca_topic_score_gemma":0.004938065,"domain_scores_codex":[0.9999273,0.000007906842,0.000005254329,0.00001612994,0.00002806196,0.00001539327],"domain_scores_gemma":[0.9999222,0.000009961921,0.00002692183,0.000006213664,0.000006541929,0.00002814396],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002083532,0.000004733567,0.00009167875,0.000007605028,0.000001292694,0.00003560395,0.000002842984,0.00002837633,0.9995408,0.00003756111,0.00002365635,0.0002049342],"study_design_scores_gemma":[0.00001060656,0.00005573167,0.009070989,0.00000715356,0.00001244032,0.0002597974,0.00001827748,0.001440492,0.987143,0.00005701871,0.001916955,0.000007548837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946184,0.0005315834,0.002114961,0.00009869175,0.00002321752,0.00001717429,0.0004663585,0.0002010407,0.001928626],"genre_scores_gemma":[0.9944636,0.0002863797,0.002052663,0.00008103627,0.000005183549,0.00002492599,0.000606489,0.00008303824,0.002396584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001920997,"threshold_uncertainty_score":0.004001677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008250088318797998,"score_gpt":0.1989144206838963,"score_spread":0.1906643323650982,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}