{"id":"W2123632312","doi":"10.1016/j.taap.2005.01.061","title":"Molecular and biochemical mechanisms in teratogenesis involving reactive oxygen species","year":2005,"lang":"en","type":"review","venue":"Toxicology and Applied Pharmacology","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":234,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"University of Toronto; Massachusetts General Hospital; Harvard University; Pfizer","keywords":"DNA damage; Reactive oxygen species; Oxidative stress; Glutathione; DNA repair; Biochemistry; Chemistry; Knockout mouse; Cell biology; Biology; Enzyme; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005065299,0.0011517,0.001255429,0.001490925,0.0002980533,0.0007606416,0.001086947,0.001018269,0.002387417],"category_scores_gemma":[0.0003562417,0.0003098693,0.0003439908,0.001630349,0.0006176794,0.001348536,0.0005248459,0.00139059,0.001920786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005178438,"about_ca_system_score_gemma":0.0009472651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008515607,"about_ca_topic_score_gemma":0.001498714,"domain_scores_codex":[0.9998893,0.00001315513,0.00001885899,0.00002052205,0.0000482436,0.00000998603],"domain_scores_gemma":[0.9998216,0.00006216302,0.00003125706,0.000009682753,0.00005985359,0.00001548141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001265222,0.0001435293,0.0002460632,0.007520686,0.00006758807,0.0004281743,0.00005418934,0.0007738512,0.008399215,0.004844201,0.02039675,0.9569993],"study_design_scores_gemma":[0.00002907198,0.0001403038,0.001119719,0.001436519,0.0001893287,0.002183309,0.00006904301,0.0002526852,0.004214203,0.005720404,0.9846159,0.00002962917],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002683749,0.9959901,0.0009954487,0.0003155583,0.0004042274,0.00001204821,0.00002194066,0.00002030485,0.001972024],"genre_scores_gemma":[0.0008986812,0.9965851,0.000611775,0.0001425588,0.0002546923,0.00001013414,0.00002819685,0.000001174616,0.001467674],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002387417,"threshold_uncertainty_score":0.007986665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04470394394229046,"score_gpt":0.346211512087266,"score_spread":0.3015075681449755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}