{"id":"W2123647733","doi":"10.1016/j.cell.2012.02.013","title":"Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family","year":2012,"lang":"en","type":"article","venue":"Cell","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1752,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; Ontario Institute for Cancer Research; University of Toronto; Lunenfeld-Tanenbaum Research Institute; Structural Genomics Consortium","funders":"Canada Research Chairs; Canadian Institutes of Health Research; Genome Canada; Wellcome Trust; GlaxoSmithKline; Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada; Pfizer; Eli Lilly and Company","keywords":"Bromodomain; Acetylation; Biology; BRD4; Histone; Computational biology; Genetics; Structural similarity; BET inhibitor; Epigenetics; Biochemistry; DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01339970949480928,"score_gpt":0.2479835714959281,"score_spread":0.2345838620011188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}