{"id":"W2123717856","doi":"10.1021/bm060073w","title":"RGD Conjugation to Polyethyleneimine Does Not Improve DNA Delivery to Bone Marrow Stromal Cells","year":2006,"lang":"en","type":"article","venue":"Biomacromolecules","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Transfection; Chemistry; Gene delivery; Stromal cell; Genetic enhancement; Integrin; Ethylene glycol; Molecular biology; Bone marrow; Reporter gene; Conjugated system; Biophysics; Biochemistry; Cell biology; Gene; Cancer research; Cell; Polymer; Biology; Gene expression; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002786278,0.0003231381,0.0002395196,0.0001783592,0.00007468075,0.0003163986,0.0001557447,0.0002129265,0.0007330435],"category_scores_gemma":[0.00034073,0.00014361,0.0001257767,0.0001308539,0.0001691576,0.0002086392,0.0001386353,0.0002326391,0.000395296],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002558644,"about_ca_system_score_gemma":0.0002327858,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004866273,"about_ca_topic_score_gemma":0.0007401088,"domain_scores_codex":[0.9997988,0.00003598221,0.00002200852,0.00003470909,0.00007829665,0.00003018323],"domain_scores_gemma":[0.9997881,0.00008088603,0.00004154129,0.00002356638,0.00003982384,0.00002607046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000242049,0.000005238481,0.0001346146,0.00002747667,0.000003760542,0.00002914321,0.00001310339,0.00005675376,0.9980528,0.00006298951,0.00002092379,0.001569083],"study_design_scores_gemma":[0.00000383435,0.00008638258,0.0008110652,0.000001764661,0.000007453723,0.00009912712,0.000005753604,0.0002543578,0.9965852,0.00001202559,0.002131409,0.000001596783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890644,0.001608828,0.006507278,0.0001122836,0.00003800657,0.00002891715,0.0001411333,0.0001326642,0.002366448],"genre_scores_gemma":[0.9899809,0.0009337899,0.004287021,0.00005123883,0.000008676496,0.00001969412,0.0003760522,0.00003944893,0.004303013],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007330435,"threshold_uncertainty_score":0.002452314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00552588484718518,"score_gpt":0.2189986625188499,"score_spread":0.2134727776716647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}