{"id":"W2123717856","doi":"10.1021/bm060073w","title":"RGD Conjugation to Polyethyleneimine Does Not Improve DNA Delivery to Bone Marrow Stromal Cells","year":2006,"lang":"en","type":"article","venue":"Biomacromolecules","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Transfection; Chemistry; Gene delivery; Stromal cell; Genetic enhancement; Integrin; Ethylene glycol; Molecular biology; Bone marrow; Reporter gene; Conjugated system; Biophysics; Biochemistry; Cell biology; Gene; Cancer research; Cell; Polymer; Biology; Gene expression; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001165251,0.0003017577,0.000219683,0.0001331233,0.0001007316,0.00008687847,0.0002944215,0.0001903211,0.00004127521],"category_scores_gemma":[0.00002791324,0.0002644056,0.0001451273,0.0001369267,0.00005918154,0.000008712614,0.0002216577,0.0000570206,0.0002153474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003051001,"about_ca_system_score_gemma":0.00006044961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004822839,"about_ca_topic_score_gemma":0.00044174,"domain_scores_codex":[0.9982536,0.00004972674,0.0003573067,0.0006591515,0.0002155237,0.0004647174],"domain_scores_gemma":[0.9990649,0.00001100801,0.00009131824,0.0004676529,0.00017321,0.000191966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002728192,0.00008383803,0.0001470964,0.00001373483,0.00003466508,0.00002968621,0.00002626812,0.00002203549,0.9907739,0.00004740732,0.005764676,0.002783942],"study_design_scores_gemma":[0.0003930869,0.0007636591,0.001761842,0.00001944313,0.00002373137,0.00001177786,0.00005976158,0.00001564033,0.988387,0.00003335987,0.008131128,0.0003995299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995688,0.000212153,0.001640434,0.00068977,0.0004630112,0.0003602946,0.0004097932,0.00003679174,0.000499782],"genre_scores_gemma":[0.9925029,0.00002367515,0.002269002,0.001457895,0.0005444409,0.00005308517,0.0002531712,0.00004161092,0.002854212],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003185063,"threshold_uncertainty_score":0.9999808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00552588484718518,"score_gpt":0.2189986625188499,"score_spread":0.2134727776716647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}