{"id":"W2123730796","doi":"10.1128/jb.00327-07","title":"Kinetics of Polynucleotide Phosphorylase: Comparison of Enzymes from <i>Streptomyces</i> and <i>Escherichia coli</i> and Effects of Nucleoside Diphosphates","year":2007,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Emory University; National Science Foundation","keywords":"Polynucleotide phosphorylase; Phosphorolysis; Streptomyces coelicolor; Purine nucleoside phosphorylase; Escherichia coli; Biology; Enzyme; Biochemistry; Streptomyces; Nucleoside; Genetics; Bacteria; Purine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002024925,0.0001461614,0.0005492652,0.0000568102,0.0000147244,0.000005148768,0.0001730901,0.0002177474,0.000008769433],"category_scores_gemma":[0.000202155,0.0001227872,0.0001062838,0.00007337625,0.0004745646,0.00000524797,0.0001594993,0.0001685175,1.492124e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000533715,"about_ca_system_score_gemma":0.00003068852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006625328,"about_ca_topic_score_gemma":0.00001234902,"domain_scores_codex":[0.9987466,0.00007624981,0.0006693031,0.0001705569,0.0001394808,0.000197843],"domain_scores_gemma":[0.9987464,0.0001461112,0.0006077742,0.0001656774,0.0001985916,0.0001354373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007509618,0.0001918484,0.03262068,0.0001432446,0.0001730505,0.000008892723,0.00007565479,0.00000117516,0.9629013,0.00002524006,0.0002296325,0.002878344],"study_design_scores_gemma":[0.0009815656,0.001748279,0.06064573,0.00008381808,0.00006732901,0.00001953323,0.00006930524,0.000003582561,0.9341717,0.00004682839,0.002067577,0.00009473805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798836,0.0194536,0.0003415292,0.0000646181,0.00009229804,0.00009340006,0.0000215842,0.000001349538,0.00004806466],"genre_scores_gemma":[0.9964498,0.001318535,0.002032521,0.00009614926,0.00006364669,6.683316e-7,0.00001264934,0.00001485243,0.00001123512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02872957,"threshold_uncertainty_score":0.5007116,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005537219522438038,"score_gpt":0.2566110612040793,"score_spread":0.2510738416816413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}