{"id":"W2123747786","doi":"10.1200/jco.2004.09.122","title":"Acetaminophen (Paracetamol) Improves Pain and Well-Being in People With Advanced Cancer Already Receiving a Strong Opioid Regimen: A Randomized, Double-Blind, Placebo-Controlled Cross-Over Trial","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Pain Management and Opioid Use","field":"Medicine","cited_by":127,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Acetaminophen; Placebo; Regimen; Opioid; Randomized controlled trial; Cancer pain; Anesthesia; Cancer; Internal medicine; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002133671,0.001189657,0.00282382,0.0004887317,0.0006205855,0.000896375,0.0008180271,0.00227672,0.005720512],"category_scores_gemma":[0.002837654,0.0007813355,0.001837149,0.0004684946,0.001061765,0.0008130218,0.0004268692,0.001982134,0.0006282874],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004484624,"about_ca_system_score_gemma":0.0008003208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007666945,"about_ca_topic_score_gemma":0.001508405,"domain_scores_codex":[0.9990655,0.0005222317,0.0001029638,0.0001322145,0.00008375412,0.00009335288],"domain_scores_gemma":[0.9983838,0.0006388793,0.0003643067,0.00009815112,0.0001374581,0.0003774166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9729671,0.009304009,0.0005751692,0.00135732,0.00126608,0.00003107586,0.00004484892,0.00009841909,0.001622227,0.00003256095,0.0002273523,0.01247386],"study_design_scores_gemma":[0.9350547,0.06245628,0.001353532,0.00004658207,0.0005466784,0.00001445516,0.00001254507,0.00009965505,0.0001810888,0.00002853692,0.000200046,0.000005854645],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9824356,0.009857371,0.0004544024,0.0006026173,0.000736259,0.004224612,0.0004603284,0.00007440159,0.001154268],"genre_scores_gemma":[0.9853745,0.006453648,0.001307087,0.0008438712,0.0008141228,0.00367311,0.0003493119,0.00001196346,0.001172437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005720512,"threshold_uncertainty_score":0.01913708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03814570226977681,"score_gpt":0.4066347349781842,"score_spread":0.3684890327084074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}