{"id":"W2123776180","doi":"10.1016/j.lfs.2006.10.006","title":"Physiological and therapeutic factors affecting cholesterol metabolism: Does a reciprocal relationship between cholesterol absorption and synthesis really exist?","year":2006,"lang":"en","type":"review","venue":"Life Sciences","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; McGill University","funders":"","keywords":"Lathosterol; Ezetimibe; Cholesterol; Internal medicine; Cholesterol synthesis; Endocrinology; Absorption (acoustics); Metabolism; ABCA1; Chemistry; Biology; Biochemistry; Campesterol; Sterol; Medicine; Materials science; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001361985,0.001105707,0.003434505,0.001376162,0.000403044,0.001624956,0.001438093,0.002059311,0.003244655],"category_scores_gemma":[0.001245761,0.0003266842,0.0004732713,0.002463913,0.001379146,0.002453092,0.0008507064,0.002718491,0.002243125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000673009,"about_ca_system_score_gemma":0.001541944,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001018873,"about_ca_topic_score_gemma":0.002154053,"domain_scores_codex":[0.9997446,0.00005749026,0.00004578263,0.00004420586,0.00008344586,0.00002453711],"domain_scores_gemma":[0.9993069,0.0004156298,0.00006093105,0.00002588584,0.0001412324,0.00004938955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001756078,0.0001213349,0.0003194997,0.01365982,0.0001707597,0.0003669386,0.00009120046,0.0002018312,0.001714703,0.006176691,0.02880937,0.9481921],"study_design_scores_gemma":[0.000064131,0.0001283171,0.001697543,0.005179645,0.0002772504,0.001904376,0.0002221199,0.00008988564,0.0006676139,0.00546168,0.9842668,0.0000406678],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007499605,0.9983387,0.0001414504,0.000642088,0.0002796563,0.0000021641,0.000007852323,0.000005061782,0.0005079532],"genre_scores_gemma":[0.0004609857,0.9985483,0.0002024521,0.0003294909,0.0002505523,0.000004205107,0.00001133153,9.566609e-7,0.0001917087],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003434505,"threshold_uncertainty_score":0.01085448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1445295201120763,"score_gpt":0.3683232365797221,"score_spread":0.2237937164676458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}