{"id":"W2123783570","doi":"10.1093/hmg/9.10.1495","title":"Loss of DAL-1, a protein 4.1-related tumor suppressor, is an important early event in the pathogenesis of meningiomas","year":2000,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Neurofibromatosis and Schwannoma Cases","field":"Medicine","cited_by":182,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; National Cancer Institute; University of Pennsylvania; University of Toronto; Mayo Clinic","keywords":"Biology; Moesin; Merlin (protein); Carcinogenesis; Loss of heterozygosity; Radixin; Tumor suppressor gene; Cancer research; Ezrin; Meningioma; Pathogenesis; Neurofibromatosis type 2; Pathology; Genetics; Neurofibromatosis; Cancer; Gene; Cell; Immunology; Allele; Suppressor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008143929,0.0003064557,0.0001723604,0.0004203592,0.0001756513,0.0001954185,0.0001236772,0.000180292,0.0006295491],"category_scores_gemma":[0.0001496165,0.0001022507,0.0001317869,0.00009684038,0.0001791605,0.0001240393,0.0001813353,0.0002523467,0.0002305531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003398905,"about_ca_system_score_gemma":0.0001484317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005817525,"about_ca_topic_score_gemma":0.0006066369,"domain_scores_codex":[0.9999226,0.000005517998,0.000005753964,0.00001617966,0.00003144092,0.00001842593],"domain_scores_gemma":[0.9999332,0.00000661246,0.00003151652,0.000004681863,0.000007728007,0.00001625703],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001273642,0.00001448168,0.008518966,0.00002301888,0.000007749512,0.0003935379,0.00001890831,0.00004437442,0.9874479,0.00006503127,0.00005351954,0.003285103],"study_design_scores_gemma":[0.00001441874,0.0002638584,0.1626419,0.000008590923,0.00004489014,0.005257419,0.00007299256,0.0008571634,0.8229308,0.0001546675,0.007746426,0.000006775213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969354,0.001459722,0.0008960821,0.00004894405,0.000007327977,0.000006965317,0.000125984,0.00004260036,0.0004769479],"genre_scores_gemma":[0.9974976,0.0005570761,0.0004919007,0.00001382832,0.000004508983,0.000007289413,0.0002107469,0.000004665954,0.001212254],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006295491,"threshold_uncertainty_score":0.002466142,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01596478917651185,"score_gpt":0.2638783972340925,"score_spread":0.2479136080575807,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}