{"id":"W2123797251","doi":"10.1371/journal.pone.0030048","title":"Microarray Analysis of HIV Resistant Female Sex Workers Reveal a Gene Expression Signature Pattern Reminiscent of a Lowered Immune Activation State","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Public Health Agency of Canada; University of Manitoba","funders":"Canadian Institutes of Health Research; Bill and Melinda Gates Foundation","keywords":"Biology; Fold change; KEGG; Transcriptome; Gene; Gene expression; Microarray; Microarray analysis techniques; Gene expression profiling; Biological pathway; Signal transduction; Pentose phosphate pathway; Molecular biology; Genetics; Glycolysis; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001232893,0.0001268306,0.0002250339,0.0003704396,0.0002759918,0.0002526611,0.00009236254,0.0001952766,0.001506017],"category_scores_gemma":[0.0001356155,0.00009259739,0.0001552957,0.0004181371,0.0001601342,0.00006245667,0.0001017911,0.0002102196,0.0003167318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001100341,"about_ca_system_score_gemma":0.00009767814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006542145,"about_ca_topic_score_gemma":0.001753909,"domain_scores_codex":[0.9998769,0.00001256693,0.000006920354,0.00004168957,0.00003164638,0.0000302358],"domain_scores_gemma":[0.9999408,0.00001629397,0.00001359144,0.000007347727,0.00001147581,0.00001051974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001495848,0.000017847,0.01253252,0.00002822367,0.00001030228,0.00007187117,0.0001079372,0.00002175302,0.9848015,0.00002538572,0.00007227064,0.002160829],"study_design_scores_gemma":[0.000008755291,0.0003326098,0.8693097,0.00001034825,0.00003000436,0.0005839572,0.0004155122,0.0004623166,0.1267095,0.000117019,0.002012562,0.000007704281],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970005,0.000236227,0.0009229064,0.00004776134,0.000007333595,0.00001191079,0.001004467,0.00001787404,0.0007508666],"genre_scores_gemma":[0.9916767,0.0003759773,0.00252665,0.0001000248,0.00001302139,0.00006967568,0.001773068,0.0000108095,0.003454177],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001506017,"threshold_uncertainty_score":0.005038202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02545923875502749,"score_gpt":0.2452563457174476,"score_spread":0.2197971069624201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}