{"id":"W2123949120","doi":"10.1128/mcb.00880-08","title":"Ubiquitin-Regulated Recruitment of IκB Kinase ε to the MAVS Interferon Signaling Adapter","year":2009,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Jewish General Hospital","funders":"","keywords":"Biology; MDA5; Interferon; IκB kinase; Signal transducing adaptor protein; Ubiquitin; Cell biology; Signal transduction; RIG-I; Wnt signaling pathway; Interferon regulatory factors; Transcription factor; Phosphorylation; Kinase; Mitochondrion; Virology; NF-κB; Gene; RNA; Genetics; RNA interference","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000102947,0.000215546,0.000117852,0.0001758857,0.0001758275,0.0003154381,0.0001241464,0.0001783242,0.001205993],"category_scores_gemma":[0.0001156605,0.00009621557,0.000215989,0.0001267026,0.0001702131,0.0002122781,0.0003008913,0.0002310628,0.0005871741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004560359,"about_ca_system_score_gemma":0.000122602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003538069,"about_ca_topic_score_gemma":0.0004653098,"domain_scores_codex":[0.9998924,0.00001479515,0.000008138758,0.00002585027,0.00002555547,0.00003342423],"domain_scores_gemma":[0.9999311,0.000005227709,0.00002550978,0.0000130744,0.000008764137,0.00001626282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008848675,0.00001174178,0.0008041428,0.00002246016,0.000004438025,0.0000622468,0.00001716467,0.00007688837,0.9969844,0.0002514414,0.00003173488,0.001644874],"study_design_scores_gemma":[0.00001526753,0.0001014971,0.03193653,0.00001038584,0.00001084396,0.0004046469,0.00009600278,0.001701668,0.9619306,0.0002603648,0.00352578,0.000006318509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929073,0.001646441,0.003175207,0.00006365608,0.00002026951,0.00001084152,0.0001047453,0.0000501916,0.002021468],"genre_scores_gemma":[0.9970165,0.0003854955,0.000846734,0.00002618278,0.00000502685,0.000008275481,0.0001556879,0.000005100901,0.001551042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001205993,"threshold_uncertainty_score":0.0040344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02071146008724991,"score_gpt":0.2591542785387628,"score_spread":0.2384428184515129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}