{"id":"W2123949120","doi":"10.1128/mcb.00880-08","title":"Ubiquitin-Regulated Recruitment of IκB Kinase ε to the MAVS Interferon Signaling Adapter","year":2009,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Jewish General Hospital","funders":"","keywords":"Biology; MDA5; Interferon; IκB kinase; Signal transducing adaptor protein; Ubiquitin; Cell biology; Signal transduction; RIG-I; Wnt signaling pathway; Interferon regulatory factors; Transcription factor; Phosphorylation; Kinase; Mitochondrion; Virology; NF-κB; Gene; RNA; Genetics; RNA interference","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002919098,0.0002006917,0.0003035911,0.0001115051,0.00009826075,0.00001056395,0.0002424175,0.0002187079,0.0002313731],"category_scores_gemma":[0.00003762394,0.000137427,0.0001155132,0.0000956156,0.0001676109,0.00001631568,0.0001085447,0.0001922175,0.00009637511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001671912,"about_ca_system_score_gemma":0.00002109883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003646069,"about_ca_topic_score_gemma":0.000003446259,"domain_scores_codex":[0.9985642,0.0004398923,0.0003281814,0.000300457,0.00002400348,0.0003432126],"domain_scores_gemma":[0.9994394,0.00005047734,0.0000837953,0.0003373952,0.00005960348,0.00002930237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006436962,0.00006490262,0.00001890481,0.000005102238,0.00009860341,0.00001161455,0.0003665221,0.000006067364,0.9737689,0.004666983,0.0002092291,0.02013948],"study_design_scores_gemma":[0.0005293997,0.00191046,0.0001546407,0.00003706189,0.00004083786,0.00003927568,0.0001654521,0.000004701198,0.9450709,0.0002484092,0.05164597,0.000152905],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831165,0.008961099,0.004958899,0.001562139,0.0002843241,0.0004375487,0.00001304966,0.00002887368,0.0006375319],"genre_scores_gemma":[0.9975011,0.00003484714,0.00007981401,0.001339546,0.00001498582,0.00001988695,0.00007274816,0.00001159291,0.000925453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05143674,"threshold_uncertainty_score":0.560411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02071146008724991,"score_gpt":0.2591542785387628,"score_spread":0.2384428184515129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}