{"id":"W2123957608","doi":"10.1200/jco.2012.43.4589","title":"Gene Expression–Based Model Using Formalin-Fixed Paraffin-Embedded Biopsies Predicts Overall Survival in Advanced-Stage Classical Hodgkin Lymphoma","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":196,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"Michael Smith Health Research BC; Terry Fox Foundation; Canadian Institutes of Health Research; Cancer Research Society; American Society of Hematology; National Cancer Institute; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Medicine; Internal medicine; Oncology; Dacarbazine; Hazard ratio; Proportional hazards model; Population; Bleomycin; Cohort; ABVD; Vinblastine; Chemotherapy; Confidence interval; Vincristine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001576842,0.0004981195,0.0004773476,0.0004641591,0.0001736779,0.000548725,0.0005282915,0.0003338296,0.0007353559],"category_scores_gemma":[0.002284229,0.0002235587,0.0005278916,0.0001656845,0.0004252363,0.0002269676,0.000309592,0.0004811345,0.0001706055],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005621039,"about_ca_system_score_gemma":0.0005641062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00530441,"about_ca_topic_score_gemma":0.003375883,"domain_scores_codex":[0.9997643,0.0001078565,0.000007799113,0.00006876882,0.00002077293,0.00003066716],"domain_scores_gemma":[0.9989902,0.0007278507,0.000133712,0.00003642406,0.00007256373,0.00003922584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"observational","study_design_scores_codex":[0.0009088137,0.0001971068,0.1367113,0.00004314478,0.0003311177,0.0002391043,0.00006594774,0.8412962,0.002689688,0.0007032118,0.0005972584,0.01621708],"study_design_scores_gemma":[0.00003325318,0.00009832503,0.009258787,0.000004881562,0.00003055735,0.00003834187,0.00001006139,0.9897109,0.000245349,0.0004768163,0.00008742207,0.00000544085],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9639286,0.0001889106,0.03498279,0.0002360266,0.00001163793,0.00004611805,0.0002374813,0.00009377045,0.0002747281],"genre_scores_gemma":[0.9953708,0.0000611154,0.00356883,0.00004308116,0.00001082484,0.00004595142,0.0004132426,0.000008175815,0.0004780447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00530441,"threshold_uncertainty_score":0.01054704,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1669619706314812,"score_gpt":0.4494040615140494,"score_spread":0.2824420908825681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}