{"id":"W2123959629","doi":"","title":"Interactions of grapefruit juice and cardiovascular medications: A potential risk of toxicity.","year":2003,"lang":"en","type":"article","venue":"PubMed","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"","keywords":"Grapefruit juice; Pharmacology; Bioavailability; CYP3A4; Pharmacodynamics; Pharmacokinetics; Drug; Medicine; Drug interaction; Adverse effect; Cytochrome P450; Internal medicine; Metabolism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009474317,0.0003789353,0.000854357,0.0005842861,0.00034717,0.0005552581,0.0002820274,0.001202615,0.003085214],"category_scores_gemma":[0.002122437,0.0001451285,0.0006128954,0.0004213043,0.0002208153,0.000319778,0.0003977242,0.0004881933,0.0006162234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002956633,"about_ca_system_score_gemma":0.0004075296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005680069,"about_ca_topic_score_gemma":0.00116722,"domain_scores_codex":[0.9990689,0.0004268138,0.00007134944,0.00006697957,0.0003352592,0.00003067344],"domain_scores_gemma":[0.9985327,0.0007099524,0.00040626,0.00006520531,0.0002017093,0.00008414149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001938996,0.0003244962,0.07803649,0.006548519,0.001295885,0.01526785,0.0003246529,0.0007203257,0.07168903,0.002296203,0.01132381,0.8102337],"study_design_scores_gemma":[0.000416979,0.01183749,0.3349492,0.001913071,0.002511236,0.1679906,0.0005108846,0.002432194,0.08065961,0.005495793,0.3911567,0.0001262799],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.2517048,0.7032393,0.008632452,0.007609799,0.0009518958,0.0001995893,0.000567669,0.0002040438,0.02689038],"genre_scores_gemma":[0.7965719,0.1813422,0.005580279,0.00352361,0.001400407,0.0001002335,0.0003605665,0.00003373128,0.01108709],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003085214,"threshold_uncertainty_score":0.01032108,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0629832689451676,"score_gpt":0.3531156536854806,"score_spread":0.2901323847403131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}