{"id":"W2124145402","doi":"10.1016/j.stemcr.2013.09.002","title":"Multiple Structural Maintenance of Chromosome Complexes at Transcriptional Regulatory Elements","year":2013,"lang":"en","type":"article","venue":"Stem Cell Reports","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Human Genome Research Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Cohesin; Biology; Condensin; Chromatin; Enhancer; Transcription factor; Euchromatin; Gene; Genetics; Regulation of gene expression; Cell biology; Heterochromatin; Mitosis; Chromosome segregation; Interphase; Transcriptional regulation; Chromosome","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007813953,0.0001361873,0.0001552522,0.00001933058,0.00006335794,0.00001074755,0.00009894533,0.00008290898,0.0001418823],"category_scores_gemma":[0.000003782487,0.0001261057,0.0001037576,0.00002821432,0.00007516101,0.000004116096,0.00007874982,0.00003847455,0.000006264635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003229111,"about_ca_system_score_gemma":0.00005287313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003292187,"about_ca_topic_score_gemma":0.00003985586,"domain_scores_codex":[0.9988869,0.00001803533,0.0004428351,0.0002886217,0.000156124,0.0002074664],"domain_scores_gemma":[0.9991537,0.00000424673,0.0002900353,0.0003811499,0.000102695,0.00006815451],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008933094,0.00001929726,0.02906788,0.00004912567,0.00002475529,0.000007391593,0.00003292805,0.0001216234,0.9694338,0.00002872598,0.0009265191,0.0002790517],"study_design_scores_gemma":[0.0007592127,0.0001881109,0.2201145,0.00002705862,0.00002269502,0.0002912831,0.0001423114,0.001205738,0.765788,0.0003822926,0.01068052,0.0003982701],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997997,0.0003283053,0.00006497794,0.0000144547,0.0002168946,0.000247488,0.00003580999,0.000007193966,0.001087864],"genre_scores_gemma":[0.9954991,0.000021336,0.000893454,0.00003462316,0.00005270449,0.00001890221,0.0002462685,0.0000199701,0.003213642],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2036458,"threshold_uncertainty_score":0.5142441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00588625442297357,"score_gpt":0.1931946950499084,"score_spread":0.1873084406269348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}