{"id":"W2124168697","doi":"10.1242/dev.058677","title":"N-WASp is required for Schwann cell cytoskeletal dynamics, normal myelin gene expression and peripheral nerve myelination","year":2011,"lang":"en","type":"article","venue":"Development","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Toronto; Toronto General Hospital; Royal Victoria Hospital; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; Canada Research Chairs; Multiple Sclerosis Society of Canada","keywords":"Biology; Myelin; Cell biology; Cytoskeleton; Schwann cell; Wiskott–Aldrich syndrome protein; Actin; Neuroscience; Actin cytoskeleton; Cell; Central nervous system; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001248004,0.0001350078,0.00009282543,0.00003579383,0.0001501218,0.00002205155,0.00008958955,0.0001163115,0.00008373048],"category_scores_gemma":[0.00001263953,0.0001343349,0.000055863,0.00002655656,0.00001748265,0.00001029532,0.0001095167,0.00005174332,0.000007121993],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003863395,"about_ca_system_score_gemma":0.00007350458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009593375,"about_ca_topic_score_gemma":0.0000188543,"domain_scores_codex":[0.999192,0.00001578276,0.0002175334,0.0002988564,0.00008468061,0.0001911755],"domain_scores_gemma":[0.9995845,0.00000289594,0.00007850279,0.0001524705,0.000108833,0.00007279713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008880784,0.0000854639,0.0001665788,0.00002300237,0.00002483917,0.000001790814,0.0005368054,0.000002216249,0.9926676,0.0001386556,0.0008150801,0.005449226],"study_design_scores_gemma":[0.0005255614,0.000159008,0.0005085594,0.00001103556,0.000008851288,0.000007272474,0.0001666838,0.001678721,0.969458,0.00006305068,0.02721229,0.0002009683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8884559,0.0002597334,0.1094068,0.00006244708,0.0003080363,0.0002622654,0.00003615863,0.00001275096,0.001195927],"genre_scores_gemma":[0.9512894,0.00005983712,0.04555007,0.0001152059,0.000105368,0.00006845195,0.0006632233,0.00002303056,0.002125488],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06385678,"threshold_uncertainty_score":0.5478019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01546971344479021,"score_gpt":0.2278685831727821,"score_spread":0.2123988697279919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}