{"id":"W2124168697","doi":"10.1242/dev.058677","title":"N-WASp is required for Schwann cell cytoskeletal dynamics, normal myelin gene expression and peripheral nerve myelination","year":2011,"lang":"en","type":"article","venue":"Development","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Toronto; Toronto General Hospital; Royal Victoria Hospital; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; Canada Research Chairs; Multiple Sclerosis Society of Canada","keywords":"Biology; Myelin; Cell biology; Cytoskeleton; Schwann cell; Wiskott–Aldrich syndrome protein; Actin; Neuroscience; Actin cytoskeleton; Cell; Central nervous system; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008895122,0.0004585915,0.0001933457,0.0002259825,0.0002078132,0.0003040321,0.0002162249,0.0002823012,0.0006789577],"category_scores_gemma":[0.0001902228,0.0002230228,0.0001727807,0.0001408324,0.0004301016,0.0001743989,0.0002806133,0.0003640248,0.0004231992],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003450592,"about_ca_system_score_gemma":0.0002991391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009379735,"about_ca_topic_score_gemma":0.001522705,"domain_scores_codex":[0.999844,0.00002236163,0.00002165777,0.00002790253,0.00006210866,0.00002194242],"domain_scores_gemma":[0.9997512,0.00003274706,0.00009819645,0.00002299473,0.0000205257,0.00007441622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005140029,0.000005884931,0.0001801931,0.00001411545,0.00000240589,0.000165733,0.000004301146,0.00004899825,0.999149,0.00006004216,0.00001367532,0.0003042636],"study_design_scores_gemma":[0.00001029653,0.00006116539,0.006705421,0.000006227045,0.00001044305,0.0007884936,0.00002624974,0.000816252,0.9895286,0.00009187066,0.001949264,0.000005597421],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940546,0.0009072279,0.003530883,0.00007972139,0.00002142548,0.00001369449,0.0004870904,0.0001304661,0.0007749245],"genre_scores_gemma":[0.9954982,0.0003838725,0.001773827,0.00001466487,0.000004366652,0.00001611907,0.0006267732,0.00003539707,0.0016468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009379735,"threshold_uncertainty_score":0.002503633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01546971344479021,"score_gpt":0.2278685831727821,"score_spread":0.2123988697279919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}