{"id":"W2124187551","doi":"10.1146/annurev-micro-091313-103456","title":"Effects of Antibiotics on Human Microbiota and Subsequent Disease","year":2014,"lang":"en","type":"review","venue":"Annual Review of Microbiology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":300,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Antibiotics; Dysbiosis; Clostridium difficile; Pseudomembranous colitis; Biology; Inflammatory bowel disease; Gut flora; Colonisation resistance; Disease; Immunology; Microbiology; Roseburia; Medicine; Bacteria; Bacteroides; Genetics; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005023968,0.0008083758,0.001064661,0.001611706,0.0002795703,0.001026188,0.0006288796,0.001170527,0.0040703],"category_scores_gemma":[0.000699052,0.000213252,0.0004027832,0.001442143,0.0005113534,0.0008438179,0.0008462645,0.001251106,0.00300373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005645036,"about_ca_system_score_gemma":0.001034909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009363252,"about_ca_topic_score_gemma":0.001391668,"domain_scores_codex":[0.9997333,0.00004924311,0.00003303253,0.00003787892,0.0001152733,0.00003137021],"domain_scores_gemma":[0.9997229,0.00008695678,0.00005235892,0.00001254367,0.00008311278,0.00004218616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007746175,0.00005632641,0.0003618705,0.01093798,0.00007375313,0.0002382847,0.00006993295,0.0002172085,0.004030302,0.004105368,0.02360748,0.9562241],"study_design_scores_gemma":[0.00001100794,0.00009711487,0.001171375,0.00211027,0.00006201053,0.001300014,0.00005053782,0.00004502615,0.001107443,0.001578916,0.9924502,0.00001605445],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001560676,0.9981757,0.000130118,0.0002624451,0.0001981769,0.000004162664,0.00001938271,0.00001011415,0.001043724],"genre_scores_gemma":[0.0009693131,0.9979218,0.0001467828,0.0001280041,0.0001638852,0.000005541538,0.0000212296,0.000001733996,0.0006416346],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0040703,"threshold_uncertainty_score":0.01361656,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01458331608902317,"score_gpt":0.3422990989767988,"score_spread":0.3277157828877756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}