{"id":"W2124245160","doi":"10.2174/1381612033454621","title":"Plasminogen Activator Inhibitor-1 in Tumor Growth, Angiogenesis and Vascular Remodeling","year":2003,"lang":"en","type":"review","venue":"Current Pharmaceutical Design","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":171,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Vitronectin; Angiogenesis; Plasminogen activator; Plasminogen activator inhibitor-1; Fibrinolysis; Cancer research; Tissue plasminogen activator; Extracellular matrix; Neovascularization; T-plasminogen activator; Angiogenesis inhibitor; Endocrinology; Fibrin; Endothelial stem cell; Biology; Chemistry; Internal medicine; Cell biology; Immunology; Medicine; In vitro; Biochemistry; Fibronectin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000660593,0.0006685944,0.001007855,0.0001993717,0.00008727038,0.00005475201,0.0003003433,0.0004231075,0.00002407605],"category_scores_gemma":[0.0001584502,0.0006072506,0.0004741374,0.000270517,0.00008365387,0.00001256229,0.0002084821,0.0004914392,0.00003226818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007843881,"about_ca_system_score_gemma":0.0003971671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001205482,"about_ca_topic_score_gemma":1.427425e-7,"domain_scores_codex":[0.9967225,0.0006915831,0.0006699793,0.001022625,0.0002741745,0.0006191871],"domain_scores_gemma":[0.9989477,0.00005915906,0.0001724408,0.0003895329,0.00006812087,0.0003630454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008405145,0.0004237806,0.000009562446,0.01023781,0.000322309,0.00003894185,0.00001396185,0.000005813614,0.02473,0.0002287902,0.002468208,0.9614367],"study_design_scores_gemma":[0.0006714271,0.0001278144,2.305259e-7,0.002667303,0.0005422888,0.00005331028,0.000002893512,0.0001275482,0.05580458,0.0001106487,0.9391067,0.0007852367],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002656117,0.991515,0.006128554,0.000004761941,0.0006003317,0.001375461,0.00004283728,0.00002289968,0.00004455753],"genre_scores_gemma":[0.0003453687,0.9975409,0.0009568427,0.00008415375,0.0005264775,0.0003051588,0.0001174791,0.0001063576,0.00001729454],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9606515,"threshold_uncertainty_score":0.9996379,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1035247771754746,"score_gpt":0.3608683700920485,"score_spread":0.2573435929165738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}