{"id":"W2124276708","doi":"10.2337/diabetes.51.3.631","title":"C2-Ceramide Influences the Expression and Insulin-Mediated Regulation of Cyclic Nucleotide Phosphodiesterase 3B and Lipolysis in 3T3-L1 Adipocytes","year":2002,"lang":"en","type":"article","venue":"Diabetes","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Lipolysis; Ceramide; Endocrinology; Insulin resistance; Internal medicine; Troglitazone; Insulin; Phosphodiesterase; Adipose tissue; Second messenger system; 3T3-L1; Adipocyte; Biology; Chemistry; Biochemistry; Medicine; Enzyme; Peroxisome proliferator-activated receptor; Receptor; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001772043,0.0004260109,0.0003803348,0.0003278402,0.0002161406,0.0003776788,0.0001785389,0.0003350405,0.001328916],"category_scores_gemma":[0.0001300678,0.000232814,0.000436915,0.0002627742,0.0003837371,0.0002806275,0.0002284361,0.0007864963,0.0004090446],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004856143,"about_ca_system_score_gemma":0.0002486358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002074411,"about_ca_topic_score_gemma":0.002227861,"domain_scores_codex":[0.9998333,0.00002882223,0.00001654228,0.00003542302,0.00003488966,0.00005085682],"domain_scores_gemma":[0.9999042,0.00002036533,0.00002258493,0.000008575193,0.00001270021,0.00003158477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004414186,0.00003153229,0.00008891815,0.00002211124,0.000004348542,0.00006245592,0.00002026535,0.00003281308,0.9988933,0.00003080065,0.00002482217,0.0003471495],"study_design_scores_gemma":[0.0001041621,0.0005542035,0.009810131,0.00001037728,0.00003093927,0.0002558785,0.0001085573,0.0009289773,0.98618,0.00009345086,0.001907794,0.00001556776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926425,0.003667226,0.001015834,0.0001642495,0.00006844697,0.00003249316,0.0006741032,0.00004157112,0.00169367],"genre_scores_gemma":[0.9932584,0.001970901,0.001241402,0.0002110986,0.00002885503,0.00007765392,0.0007789666,0.00003053037,0.002402222],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002074411,"threshold_uncertainty_score":0.004445672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007801585924471552,"score_gpt":0.2067471136662406,"score_spread":0.198945527741769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}