{"id":"W2124276708","doi":"10.2337/diabetes.51.3.631","title":"C2-Ceramide Influences the Expression and Insulin-Mediated Regulation of Cyclic Nucleotide Phosphodiesterase 3B and Lipolysis in 3T3-L1 Adipocytes","year":2002,"lang":"en","type":"article","venue":"Diabetes","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Lipolysis; Ceramide; Endocrinology; Insulin resistance; Internal medicine; Troglitazone; Insulin; Phosphodiesterase; Adipose tissue; Second messenger system; 3T3-L1; Adipocyte; Biology; Chemistry; Biochemistry; Medicine; Enzyme; Peroxisome proliferator-activated receptor; Receptor; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001014627,0.0001016703,0.0001280622,0.00004181575,0.00005420795,0.00001959947,0.00007040225,0.00007493763,0.00002152814],"category_scores_gemma":[0.0001447192,0.00007391605,0.00002418478,0.00009509372,0.0001174325,0.00001026875,0.00006533771,0.00005342999,0.000001081473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002794312,"about_ca_system_score_gemma":0.000004466078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003296636,"about_ca_topic_score_gemma":0.000005251657,"domain_scores_codex":[0.9993731,0.00005364713,0.0001881683,0.0001815812,0.00007135743,0.00013218],"domain_scores_gemma":[0.9996181,0.00009069798,0.00008708708,0.0001416444,0.00002724848,0.00003518121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001331716,0.0000247061,0.169716,0.0000213684,0.0000185658,5.035472e-7,0.000268597,0.00009700449,0.8271695,0.000005794933,0.0003198868,0.00234475],"study_design_scores_gemma":[0.0004880482,0.00008652805,0.1410594,0.00007335067,0.00002088089,8.208964e-7,0.0001125014,0.001148758,0.8558679,0.0001006944,0.0009114639,0.0001296731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9701651,0.02951078,0.00000327609,0.0001313175,0.00001922622,0.00008062128,0.000006918017,0.000005695274,0.0000770886],"genre_scores_gemma":[0.9980371,0.001557588,0.0001078354,0.000162269,0.00005055819,0.00001105746,0.00002270099,0.000008643032,0.00004226167],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02869838,"threshold_uncertainty_score":0.3014209,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007801585924471552,"score_gpt":0.2067471136662406,"score_spread":0.198945527741769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}