{"id":"W2124303396","doi":"10.1111/j.1538-7836.2006.02164.x","title":"Multiple B‐cell clones producing antibodies directed to the spacer and disintegrin/thrombospondin type‐1 repeat 1 (TSP1) of ADAMTS13 in a patient with acquired thrombotic thrombocytopenic purpura","year":2006,"lang":"en","type":"article","venue":"Journal of Thrombosis and Haemostasis","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Trombosestichting Nederland; Mach-Gaensslen Foundation of Canada; Landsteiner Foundation for Blood Transfusion Research","keywords":"ADAMTS13; Disintegrin; Thrombospondin; Antibody; Molecular biology; Thrombotic thrombocytopenic purpura; Chemistry; Epitope; Immunoglobulin light chain; Monoclonal antibody; Phage display; Biology; Metalloproteinase; Biochemistry; Immunology; Platelet; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003780046,0.001165969,0.0006064316,0.00115834,0.001004906,0.0008332505,0.0009421482,0.002443802,0.002857031],"category_scores_gemma":[0.001203069,0.0005483099,0.0005874492,0.0007272575,0.0007040661,0.0004255863,0.0004175963,0.001730099,0.0007604611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000730668,"about_ca_system_score_gemma":0.0002331119,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002321086,"about_ca_topic_score_gemma":0.001291963,"domain_scores_codex":[0.9995615,0.00005860369,0.00004598383,0.0001289196,0.00007348041,0.0001314051],"domain_scores_gemma":[0.9990783,0.0006050914,0.00006000952,0.00005785078,0.00005914162,0.0001395612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.003069163,0.001906572,0.05890247,0.0003083868,0.0002840428,0.5579637,0.001630689,0.0007494643,0.3482305,0.001341241,0.002529467,0.02308439],"study_design_scores_gemma":[0.001243315,0.004128663,0.1351909,0.00007356067,0.0007449131,0.7849187,0.0007087744,0.002879936,0.0611974,0.000620042,0.008230938,0.00006284512],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915912,0.0009326216,0.0009072338,0.0005832058,0.0001041998,0.00007900105,0.0002099943,0.00007472667,0.005517733],"genre_scores_gemma":[0.9974793,0.000312748,0.0005098403,0.0003838368,0.00006849574,0.00002157391,0.0001576659,0.00001994077,0.00104663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002857031,"threshold_uncertainty_score":0.009557724,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02487580129068794,"score_gpt":0.265234960527463,"score_spread":0.2403591592367751,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}