{"id":"W2124395184","doi":"10.1093/jac/45.1.9","title":"Chromosomal beta-lactamase is packaged into membrane vesicles and secreted from Pseudomonas aeruginosa","year":2000,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":314,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Pseudomonas aeruginosa; Vesicle; Microbiology; Secretion; Enzyme; Bacterial outer membrane; Biology; Bacteria; Cystic fibrosis; Extracellular; Membrane; Chemistry; Biochemistry; Gene; Genetics; Escherichia coli","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009121175,0.0002749064,0.0002388555,0.0002422208,0.0002486361,0.0004869213,0.0001048954,0.0003534382,0.0004044356],"category_scores_gemma":[0.0005000751,0.0001944107,0.0002252644,0.0001882052,0.0002427806,0.0002689058,0.0003436124,0.0003718261,0.0002198079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002128715,"about_ca_system_score_gemma":0.0001428036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006520455,"about_ca_topic_score_gemma":0.00053273,"domain_scores_codex":[0.9998432,0.00002156661,0.00001623593,0.00002899493,0.00004905615,0.00004086033],"domain_scores_gemma":[0.9998009,0.00004510625,0.00004865117,0.00002204917,0.00004509206,0.00003828125],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001031888,0.000007472933,0.005723301,0.00003500862,0.00001406362,0.0002950951,0.00009222935,0.00002885583,0.9918188,0.00004651216,0.00002486672,0.001810553],"study_design_scores_gemma":[0.00005498329,0.0007284704,0.1677331,0.00004795504,0.00009933019,0.008297453,0.0008545311,0.001114833,0.8174008,0.0004166011,0.003223668,0.00002822615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982525,0.0006284293,0.0007595827,0.00006169222,0.000007423118,0.000005529593,0.00008453236,0.000009799198,0.000190608],"genre_scores_gemma":[0.9986671,0.0002883259,0.0005083615,0.000024643,0.00000599003,0.00000570724,0.0002070006,0.000007478967,0.0002853053],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006520455,"threshold_uncertainty_score":0.001544535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005029964899438209,"score_gpt":0.2227657431473369,"score_spread":0.2177357782478987,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}