{"id":"W2124413887","doi":"10.3390/ijms9060943","title":"Cloning, Expression, Purification and Crystallization of the PR Domain of Human Retinoblastoma Protein-Binding Zinc Finger Protein 1 (RIZ1)","year":2008,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"College of Pharmacy and Nutrition, University of Saskatchewan; Cancer Research Society; University of Saskatchewan","keywords":"Zinc finger; Retinoblastoma; LIM domain; RING finger domain; Biology; Amino acid; Protein domain; Gene; Recombinant DNA; Peptide sequence; Cloning (programming); Molecular biology; Chemistry; Genetics; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004832803,0.0004298226,0.0006731851,0.000321412,0.0004627361,0.000405383,0.0008547572,0.000396838,0.0008711456],"category_scores_gemma":[0.0005229363,0.0004128837,0.0004281878,0.0008631468,0.0002827761,0.0003434494,0.0003270129,0.0008958785,0.001086222],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001284759,"about_ca_system_score_gemma":0.0007937435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004642291,"about_ca_topic_score_gemma":0.005636767,"domain_scores_codex":[0.9998117,0.00002920883,0.00001614354,0.00003841453,0.00006752893,0.00003707164],"domain_scores_gemma":[0.9998572,0.00003282934,0.00002936206,0.00001823067,0.00003440714,0.00002802383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003986282,0.0001932805,0.001020248,0.0003146214,0.00003053704,0.0003598583,0.0002193104,0.003161584,0.9851285,0.001351565,0.000807017,0.007015014],"study_design_scores_gemma":[0.0002248977,0.0002454052,0.007506501,0.00003635609,0.00006639244,0.001022646,0.0001992376,0.01059026,0.9554006,0.0006833988,0.02398912,0.00003524983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9354276,0.004890828,0.04752022,0.000961346,0.00008676456,0.0006051165,0.006497394,0.0003720875,0.003638671],"genre_scores_gemma":[0.8363541,0.005853382,0.1226512,0.0001449559,0.00005008793,0.0003895673,0.02504455,0.0002264362,0.009285677],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004642291,"threshold_uncertainty_score":0.00932163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01540562723033211,"score_gpt":0.2611852179012714,"score_spread":0.2457795906709392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}