{"id":"W2124457777","doi":"10.1128/iai.71.7.3844-3851.2003","title":"Induction of Protective Immunity against<i>Schistosoma mansoni</i>via DNA Priming and Boosting with the Large Subunit of Calpain (Sm-p80): Adjuvant Effects of Granulocyte-Macrophage Colony-Stimulating Factor and Interleukin-4","year":2003,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Parasites and Host Interactions","field":"Immunology and Microbiology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Ste. Anne's Hospital","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Texas Tech University Health Sciences Center","keywords":"Biology; DNA vaccination; Immunogenicity; Immune system; Immunology; Schistosoma mansoni; Immunity; Virology; Schistosomiasis; Microbiology; Immunization; Helminths","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023695,0.0008316985,0.0003688111,0.0003602437,0.0001089546,0.0002395774,0.0003276352,0.0006057543,0.001074397],"category_scores_gemma":[0.0002419411,0.0002127027,0.000339478,0.0001232589,0.0005836878,0.0003522933,0.0002157796,0.001038552,0.0002297029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002904312,"about_ca_system_score_gemma":0.000309068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004060732,"about_ca_topic_score_gemma":0.0005523697,"domain_scores_codex":[0.9997999,0.00003720001,0.00001455715,0.00004328429,0.00003552739,0.00006961087],"domain_scores_gemma":[0.9997513,0.00005965211,0.00008986778,0.00001797371,0.00001865089,0.00006262896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004602387,0.000292181,0.0001853941,0.00009543364,0.000007854938,0.00003149956,0.00002462545,0.0001109434,0.996178,0.00007793621,0.00002741488,0.002508453],"study_design_scores_gemma":[0.0002343397,0.008387564,0.002659197,0.00001997109,0.00004098203,0.0001717128,0.00002376833,0.0006866725,0.9869362,0.00005386864,0.0007798209,0.000006046799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971514,0.0005843361,0.001303899,0.00010801,0.00003708477,0.00007168717,0.00007252797,0.00007841051,0.000592707],"genre_scores_gemma":[0.9942239,0.0008012381,0.003411441,0.00008909393,0.00003495436,0.00006594885,0.0002271893,0.00001540379,0.001130964],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001074397,"threshold_uncertainty_score":0.00359422,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008579054932778005,"score_gpt":0.2443350354968781,"score_spread":0.2357559805641001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}