{"id":"W2124457777","doi":"10.1128/iai.71.7.3844-3851.2003","title":"Induction of Protective Immunity against<i>Schistosoma mansoni</i>via DNA Priming and Boosting with the Large Subunit of Calpain (Sm-p80): Adjuvant Effects of Granulocyte-Macrophage Colony-Stimulating Factor and Interleukin-4","year":2003,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Parasites and Host Interactions","field":"Immunology and Microbiology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Ste. Anne's Hospital","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Texas Tech University Health Sciences Center","keywords":"Biology; DNA vaccination; Immunogenicity; Immune system; Immunology; Schistosoma mansoni; Immunity; Virology; Schistosomiasis; Microbiology; Immunization; Helminths","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004547166,0.0001922103,0.0003852774,0.0001502438,0.0005608909,0.00001252416,0.00005773878,0.0001637181,0.00001715582],"category_scores_gemma":[0.0003789153,0.0001451864,0.00005469014,0.0001834814,0.0004241964,0.0001805862,0.00007439199,0.0006315205,7.102618e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000400702,"about_ca_system_score_gemma":0.00003575985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002973194,"about_ca_topic_score_gemma":0.0004515209,"domain_scores_codex":[0.9984134,0.0008353555,0.0003427505,0.0001696316,0.00004294854,0.0001958966],"domain_scores_gemma":[0.998537,0.0006181825,0.0004395294,0.0002068946,0.0001742476,0.00002411388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003330448,0.000226833,0.07001621,0.0002837232,0.0002151467,0.000001010065,0.00457928,0.00001251298,0.9158812,0.0001257743,0.000002852089,0.008322443],"study_design_scores_gemma":[0.001838849,0.001260976,0.4964837,0.0003067917,0.0001073299,0.0001112756,0.001060841,0.00007138986,0.4981695,0.00004175747,0.0003853668,0.0001622965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961727,0.001182908,0.001574904,0.00001244002,0.0001631612,0.0005908958,0.0000239706,0.00002418384,0.0002548419],"genre_scores_gemma":[0.9996867,0.0001363314,0.00005413766,0.00001871894,0.000005452253,0.0000245521,0.00001387925,0.00001330736,0.00004696859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4264674,"threshold_uncertainty_score":0.5920531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008579054932778005,"score_gpt":0.2443350354968781,"score_spread":0.2357559805641001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}