{"id":"W2124530114","doi":"10.1016/j.bbamem.2007.07.021","title":"Structural biology of membrane-intrinsic β-barrel enzymes: Sentinels of the bacterial outer membrane","year":2007,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":134,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Health Sciences Centre; McMaster University Medical Centre","funders":"Canadian Institutes of Health Research","keywords":"Bacterial outer membrane; Periplasmic space; Porin; Biology; Biochemistry; Lipid bilayer; Outer membrane efflux proteins; Membrane; Biophysics; Cell biology; Chemistry; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00045069,0.00134655,0.002888404,0.0005223886,0.0001460736,0.00006119735,0.002318394,0.002459944,0.00008564098],"category_scores_gemma":[0.000125226,0.0009111951,0.001865698,0.001031302,0.001649423,0.00001381794,0.001302369,0.0006105848,0.00001402571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003625774,"about_ca_system_score_gemma":0.0005700117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006501452,"about_ca_topic_score_gemma":0.00002018704,"domain_scores_codex":[0.9945911,0.0005408727,0.002064436,0.001461422,0.0003926462,0.0009495674],"domain_scores_gemma":[0.9951036,0.0001279124,0.002132949,0.002176106,0.0002784036,0.0001810036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001985385,0.000154222,7.424066e-7,0.0047256,0.0009018802,0.000002928467,0.00003328751,2.727608e-7,0.963928,0.0002182091,0.0001253085,0.02971098],"study_design_scores_gemma":[0.0006452434,0.0003440377,0.00002542146,0.0008412632,0.0006660896,0.00007435572,0.00001016323,0.000001347827,0.7331158,0.00002269808,0.2635196,0.0007339572],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.6715294,0.3216091,0.000003733533,0.0002118497,0.002775598,0.001415591,0.002280926,0.00005427705,0.0001195669],"genre_scores_gemma":[0.2400666,0.7555432,0.0002218026,0.000098822,0.001402601,0.00004504455,0.002234684,0.0001841824,0.0002030545],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.4339342,"threshold_uncertainty_score":0.9999285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02760265060161055,"score_gpt":0.3004513598374924,"score_spread":0.2728487092358819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}