{"id":"W2124598727","doi":"10.1111/ajt.12838","title":"The Combination of Anti-NKG2D and CTLA-4 Ig Therapy Prolongs Islet Allograft Survival in a Murine Model","year":2014,"lang":"en","type":"article","venue":"American Journal of Transplantation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Novo Nordisk; Canada Research Chairs; Novo Nordisk UK Research Foundation; Alberta Innovates; Diabetes Research Institute Foundation","keywords":"Medicine; NKG2D; Islet; Transplantation; Combination therapy; Internal medicine; Endocrinology; CD8; Immunology; Cytotoxic T cell; Gastroenterology; Insulin; Immune system; In vitro; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005620731,0.001270463,0.0009625591,0.0008176297,0.0003396834,0.0006340472,0.0006901757,0.0007678099,0.0008600422],"category_scores_gemma":[0.0002344412,0.0003112001,0.0006584508,0.0003228785,0.0006534428,0.0007774438,0.0002746039,0.002564434,0.0003058903],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004542659,"about_ca_system_score_gemma":0.0004804833,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003668957,"about_ca_topic_score_gemma":0.0009177309,"domain_scores_codex":[0.99965,0.00007792545,0.00003187664,0.00007240779,0.00006633408,0.0001015198],"domain_scores_gemma":[0.9994165,0.00006597007,0.0001728705,0.0001001368,0.00002441388,0.0002201235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009052784,0.003380219,0.0007648283,0.000126898,0.0000896479,0.0003264453,0.00005861271,0.001320099,0.9757786,0.0003376698,0.0004851064,0.008279042],"study_design_scores_gemma":[0.001240682,0.04746839,0.004654348,0.00005459612,0.000292439,0.0012164,0.00009082261,0.00548535,0.9356902,0.0003807531,0.003385285,0.00004060677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937855,0.001524348,0.002453324,0.0002683999,0.0003082971,0.00006876729,0.0002537475,0.0001951291,0.00114255],"genre_scores_gemma":[0.9934617,0.001099426,0.002329239,0.0001098367,0.0001244574,0.00009234117,0.0003596069,0.00004393651,0.00237951],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001270463,"threshold_uncertainty_score":0.003295898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006981984739545585,"score_gpt":0.2263319179615744,"score_spread":0.2193499332220288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}