{"id":"W2124656134","doi":"10.1186/gb-2004-5-3-r15","title":"The ABC transporter gene family of Caenorhabditis elegans has implications for the evolutionary dynamics of multidrug resistance in eukaryotes","year":2004,"lang":"en","type":"article","venue":"Genome biology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":195,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; Genome British Columbia; University of British Columbia; BC Cancer Agency","funders":"","keywords":"Biology; Gene; Genome; Gene duplication; Genetics; ATP-binding cassette transporter; Caenorhabditis elegans; Computational biology; Efflux; Function (biology); Gene family; Transporter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000219773,0.0001234475,0.0002898301,0.00006613886,0.0001752257,0.000002306924,0.000226941,0.0001157208,0.000004226918],"category_scores_gemma":[0.00001571224,0.0000736422,0.0001452291,0.0001975283,0.000508199,0.00002027372,0.000007890177,0.0001117901,9.170839e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000955962,"about_ca_system_score_gemma":0.0002218856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002222348,"about_ca_topic_score_gemma":0.005396694,"domain_scores_codex":[0.9989666,0.00001918216,0.0004676017,0.0002120852,0.00006788244,0.0002666931],"domain_scores_gemma":[0.9991297,0.0001699282,0.0001395789,0.0003903662,0.0001329121,0.00003751449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001488226,0.0005225686,0.05664787,0.0003181543,0.0003845276,0.00001020896,0.002123625,0.0004733492,0.7596745,0.175395,0.00008577056,0.002876171],"study_design_scores_gemma":[0.001721854,0.0001774257,0.96392,0.00004336931,0.0001058169,0.000006427786,0.0003324432,0.00003956948,0.002959686,0.02306953,0.007506977,0.000116917],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8808423,0.02006637,0.07092895,0.02340377,0.0003409572,0.001853731,0.002061771,0.00003508137,0.0004670965],"genre_scores_gemma":[0.9926259,0.001285761,0.005168544,0.0001076097,0.00005895422,0.0001268763,0.0003571079,0.00001707932,0.0002521507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9072721,"threshold_uncertainty_score":0.3011482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01899087587123933,"score_gpt":0.2528864678780808,"score_spread":0.2338955920068415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}