{"id":"W2124734965","doi":"10.1152/ajpheart.00701.2005","title":"Cellular and molecular mechanisms underlying LPS-associated myocyte impairment","year":2005,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Myocyte; Internal medicine; Tumor necrosis factor alpha; TLR4; Endocrinology; Cardiac myocyte; Macrophage; Inflammation; Receptor; Lipopolysaccharide; Biology; Nitric oxide synthase; Immunology; Nitric oxide; Medicine; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002521665,0.000328054,0.0001758606,0.0002503569,0.0000946721,0.0001217226,0.0001559673,0.0003320774,0.001298193],"category_scores_gemma":[0.0001627906,0.0001213091,0.0001693528,0.00006689088,0.0003336825,0.0001776232,0.0003128364,0.0004042502,0.0003500681],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001415815,"about_ca_system_score_gemma":0.00008610939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001012444,"about_ca_topic_score_gemma":0.0001129924,"domain_scores_codex":[0.999867,0.00003712836,0.00001662337,0.00001688956,0.00003129522,0.00003111328],"domain_scores_gemma":[0.9998426,0.00002131733,0.00006575763,0.00001920098,0.00001835775,0.0000326602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002192086,0.00002167866,0.0005523162,0.00005448306,0.000004549728,0.0002559754,0.00000868704,0.00005874053,0.997273,0.0001036684,0.00001915916,0.001428486],"study_design_scores_gemma":[0.000118162,0.002044284,0.08341368,0.00004487175,0.00007020062,0.003265875,0.000128088,0.001923996,0.9053355,0.0008151687,0.002826951,0.00001317516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866252,0.005708359,0.005790748,0.0002479623,0.00003028896,0.00004886883,0.0002791365,0.00008924046,0.001180194],"genre_scores_gemma":[0.9946365,0.002125734,0.001707071,0.000100949,0.00002498893,0.00006284188,0.0002362943,0.000008502703,0.001097111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001298193,"threshold_uncertainty_score":0.004342854,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008800827648041647,"score_gpt":0.2202573213973317,"score_spread":0.21145649374929,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}