{"id":"W2124768646","doi":"10.4049/jimmunol.179.8.5264","title":"Dynamic Changes in Accessibility, Nuclear Positioning, Recombination, and Transcription at the <i>Ig</i> κ Locus","year":2007,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institutes of Health; University of Toronto","keywords":"Biology; Locus (genetics); Chromatin; Histone; Genetics; Gene; Molecular biology; Transcription (linguistics); Histone H3; Recombination; Enhancer; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000110471,0.00009443541,0.0001017719,0.0001540602,0.00009535707,0.000373358,0.0001586814,0.0001217266,0.0007691522],"category_scores_gemma":[0.0001450122,0.0001403355,0.000132716,0.0001057318,0.000161227,0.0001661097,0.0002195517,0.0002899792,0.0003172561],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001950001,"about_ca_system_score_gemma":0.0001048193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004234978,"about_ca_topic_score_gemma":0.0005262957,"domain_scores_codex":[0.9999156,0.000008937292,0.000005419624,0.00002953715,0.00002257722,0.00001802607],"domain_scores_gemma":[0.9998112,0.00003567133,0.00007202873,0.00002511604,0.00001933347,0.00003675943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002812484,0.000001803855,0.0007594074,0.000004004044,0.000001073819,0.00001279211,0.00001226172,0.0000214437,0.9986941,0.00003050676,0.000002457683,0.0004321148],"study_design_scores_gemma":[0.00000857869,0.0002117278,0.1329508,0.00001006941,0.00001407065,0.0005245789,0.0001224667,0.0007143116,0.8638974,0.0001443203,0.001389769,0.00001183298],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979435,0.0002537023,0.001169469,0.000008001766,0.000002281025,0.000002984264,0.0000995957,0.00002585607,0.0004946841],"genre_scores_gemma":[0.9980941,0.0001507449,0.0008336592,0.00001023955,0.000003475225,0.000008227587,0.0002418641,0.00001411854,0.0006436302],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007691522,"threshold_uncertainty_score":0.002573013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00452618878144003,"score_gpt":0.2272863286693756,"score_spread":0.2227601398879356,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}