{"id":"W2124778275","doi":"10.1093/intimm/dxq033","title":"Immunomodulation by hepatitis C virus-derived proteins: targeting human dendritic cells by multiple mechanisms","year":2010,"lang":"en","type":"article","venue":"International Immunology","topic":"Hepatitis C virus research","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Heritage Medical Research Clinic; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Immune system; NS3; Hepatitis C virus; Biology; T cell; Dendritic cell; Immunology; Cell biology; Cell; Antigen presentation; Antigen; Virology; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002022586,0.0003090845,0.0002727406,0.0001433103,0.0001007237,0.0002630221,0.0001167739,0.0002340191,0.0004896512],"category_scores_gemma":[0.00007101188,0.00006126953,0.0002437352,0.00009928111,0.0001651423,0.000156723,0.0002015786,0.0002905625,0.0001518764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000177052,"about_ca_system_score_gemma":0.0001876927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001482774,"about_ca_topic_score_gemma":0.0001936267,"domain_scores_codex":[0.9998595,0.00003586407,0.00001306651,0.00002149071,0.00003081797,0.00003914146],"domain_scores_gemma":[0.9999716,0.00000506792,0.000007037513,0.000004599535,0.000005401836,0.000006356474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003879068,0.0001383747,0.0003669134,0.0001547768,0.0000108868,0.00008723854,0.00002172654,0.0001364299,0.9851637,0.0002356555,0.00007646274,0.01321995],"study_design_scores_gemma":[0.0001160921,0.001275863,0.003369879,0.00002066284,0.00006994498,0.0005465815,0.00002385002,0.00134918,0.9852506,0.0001508268,0.007821071,0.000005454232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818402,0.01111341,0.00408531,0.0002382344,0.00008373683,0.0001187838,0.0001173794,0.00004689914,0.002356126],"genre_scores_gemma":[0.9908556,0.004841728,0.002650978,0.0001334885,0.00005781593,0.00005929507,0.00009914944,0.000007748969,0.001294192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004896512,"threshold_uncertainty_score":0.001638055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01148797277218105,"score_gpt":0.2879511291979957,"score_spread":0.2764631564258146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}