{"id":"W2124778275","doi":"10.1093/intimm/dxq033","title":"Immunomodulation by hepatitis C virus-derived proteins: targeting human dendritic cells by multiple mechanisms","year":2010,"lang":"en","type":"article","venue":"International Immunology","topic":"Hepatitis C virus research","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Heritage Medical Research Clinic; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Immune system; NS3; Hepatitis C virus; Biology; T cell; Dendritic cell; Immunology; Cell biology; Cell; Antigen presentation; Antigen; Virology; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003055194,0.0002221182,0.0002922314,0.0002213813,0.0002020126,0.00007047596,0.0004005394,0.0002888492,0.002882897],"category_scores_gemma":[0.0005734609,0.0002363174,0.0001042774,0.0001166461,0.0002083952,0.0002541141,0.0001729699,0.0008153568,0.000541059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001943394,"about_ca_system_score_gemma":0.00007726753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006356431,"about_ca_topic_score_gemma":0.0008042085,"domain_scores_codex":[0.9979709,0.0001188912,0.0005220885,0.0004465145,0.0004979438,0.0004436064],"domain_scores_gemma":[0.9988267,0.0001264617,0.0001572347,0.0003592452,0.0004323847,0.00009794599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007785039,0.0002558452,0.00489985,0.00001017037,0.0002114893,0.00003248908,0.0001032089,9.875699e-7,0.9851217,0.000835242,0.003784048,0.004667098],"study_design_scores_gemma":[0.001767349,0.0003070175,0.006362805,0.00003425529,0.0000153368,0.00003197265,0.00002694389,0.001478627,0.9443924,0.0007664429,0.0445892,0.0002275807],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879162,0.000245155,0.006570981,0.00105527,0.001293038,0.0007335048,0.0002291827,0.0001462112,0.001810422],"genre_scores_gemma":[0.9914399,0.000204163,0.004315224,0.0002867535,0.0001537001,0.0002285705,0.001285862,0.00006044044,0.002025379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04080515,"threshold_uncertainty_score":0.9980286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01148797277218105,"score_gpt":0.2879511291979957,"score_spread":0.2764631564258146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}