{"id":"W2124820536","doi":"10.1186/s12931-015-0250-2","title":"Aclidinium bromide and formoterol fumarate as a fixed-dose combination in COPD: pooled analysis of symptoms and exacerbations from two six-month, multicentre, randomised studies (ACLIFORM and AUGMENT)","year":2015,"lang":"en","type":"article","venue":"Respiratory Research","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Actavis","keywords":"Formoterol; Medicine; COPD; Placebo; Tiotropium bromide; Bronchodilator; Tolerability; Salmeterol; Population; Anticholinergic; Internal medicine; Minimal clinically important difference; Randomized controlled trial; Asthma; Adverse effect; Anesthesia; Lung; Lung function; Budesonide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0196377,0.002773778,0.01324163,0.002056285,0.0003731528,0.002161482,0.001216184,0.002231308,0.00288882],"category_scores_gemma":[0.01528943,0.001452059,0.02670184,0.002442983,0.000945251,0.001149709,0.0015508,0.001321013,0.0003373457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001142713,"about_ca_system_score_gemma":0.001231348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001499202,"about_ca_topic_score_gemma":0.003348598,"domain_scores_codex":[0.9840858,0.01057736,0.00249288,0.001323295,0.001022536,0.0004981396],"domain_scores_gemma":[0.9889099,0.004832552,0.003838753,0.001131835,0.0008074337,0.0004795877],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.5635843,0.0003420253,0.006576393,0.02242835,0.3942043,0.00009163444,0.00008610828,0.0008871317,0.002156519,0.00005002659,0.0004109752,0.009182233],"study_design_scores_gemma":[0.2811415,0.01848103,0.03341478,0.001017624,0.6624193,0.0001685873,0.00009503695,0.0007038683,0.0007731727,0.0001690311,0.001513585,0.0001025074],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6607483,0.3203512,0.00470696,0.0005714649,0.001000374,0.004981447,0.00576951,0.0002835587,0.001587213],"genre_scores_gemma":[0.9728969,0.01895174,0.002251473,0.0004341354,0.0002346772,0.002611788,0.002045147,0.00004025619,0.0005338803],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0196377,"threshold_uncertainty_score":0.1038554,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08441544698138102,"score_gpt":0.4061932745903059,"score_spread":0.3217778276089248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}