{"id":"W2124826140","doi":"10.1038/ncomms6383","title":"The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer","year":2014,"lang":"en","type":"article","venue":"Nature Communications","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":630,"is_retracted":false,"has_abstract":true,"ca_institutions":"Genome British Columbia","funders":"National Center for Advancing Translational Sciences; Weill Cornell Medical College; George Washington University; National Cancer Institute; Prostate Cancer Foundation","keywords":"Prostate cancer; Androgen receptor; Cancer research; Chromatin immunoprecipitation; Biology; Long non-coding RNA; Epigenetics; Transcriptome; Prostate; Cancer; Promoter; Gene; Gene expression; RNA; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009758364,0.0001349467,0.0001330362,0.0002342624,0.0001470269,0.0003371184,0.0001149484,0.00008347788,0.001073385],"category_scores_gemma":[0.0002149582,0.0001038657,0.0001060129,0.0002573878,0.0001606965,0.0001475012,0.0001942952,0.0002202902,0.0002545638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002507016,"about_ca_system_score_gemma":0.0002063119,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007329184,"about_ca_topic_score_gemma":0.001231111,"domain_scores_codex":[0.9999266,0.000007438717,0.000004832569,0.00002244266,0.00002818661,0.00001052287],"domain_scores_gemma":[0.9998995,0.00001233357,0.0000424357,0.000005740545,0.00001605178,0.00002384356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003073828,0.00001579303,0.01702036,0.0001958495,0.00003237138,0.000440737,0.00005799871,0.0002719785,0.9615815,0.0005484202,0.000631897,0.01889569],"study_design_scores_gemma":[0.0000366298,0.0003527127,0.4871729,0.00006297285,0.0001229127,0.004774923,0.0002201472,0.002623965,0.4727656,0.001283547,0.03054044,0.0000431624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9733964,0.01622465,0.003600711,0.0006350671,0.0001052061,0.00002810544,0.00174252,0.0001772567,0.004090118],"genre_scores_gemma":[0.9910425,0.004127874,0.001182195,0.0001207864,0.00003575392,0.000008367244,0.000806737,0.00001797076,0.002657865],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001073385,"threshold_uncertainty_score":0.003590822,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01028665942018417,"score_gpt":0.3290627670659034,"score_spread":0.3187761076457192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}