{"id":"W2124884836","doi":"10.1152/ajpcell.00390.2001","title":"Influence of calcium on myosin thick filament formation in intact airway smooth muscle","year":2002,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia; Providence Health Care","funders":"","keywords":"Protein filament; Myosin; Biophysics; Calcium; EGTA; Isometric exercise; Myosin head; Chemistry; Actin; Anatomy; Myocyte; Myosin light-chain kinase; Biology; Biochemistry; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001942877,0.0002854817,0.000662419,0.0002046705,0.00005905295,0.000003457033,0.000455632,0.0001850088,0.00008028252],"category_scores_gemma":[0.0000961609,0.000245594,0.0002351878,0.0002604552,0.0006933157,0.00002596051,0.000108308,0.0004140971,0.00002466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000365614,"about_ca_system_score_gemma":0.00004921774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006355967,"about_ca_topic_score_gemma":0.00001074903,"domain_scores_codex":[0.9978777,0.0004518121,0.0007408973,0.000364817,0.0001409917,0.000423764],"domain_scores_gemma":[0.9981706,0.0001128271,0.001014746,0.0004303048,0.0001697092,0.000101797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000789116,0.0005744867,0.0001024901,0.00003553409,0.00003822208,0.000001858233,0.0002548287,0.02672282,0.968426,0.00003737881,0.001138253,0.001878967],"study_design_scores_gemma":[0.00337065,0.01535878,0.2561418,0.0001138121,0.00004717818,0.00001828528,0.0008897074,0.000547585,0.7185285,0.001167543,0.003192262,0.0006239269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988165,0.0002443409,0.00003866216,0.0002187234,0.0001152612,0.0001446211,0.00001168626,0.000005788911,0.0004043427],"genre_scores_gemma":[0.9979122,0.0005055345,0.0001553066,0.001189945,0.0001501046,0.00001168369,0.00002787072,0.00002244813,0.00002485558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2560393,"threshold_uncertainty_score":0.9999996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008686326767162586,"score_gpt":0.2358121115984058,"score_spread":0.2271257848312432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}