{"id":"W2125028785","doi":"10.1182/blood-2006-05-023796","title":"A role for IL-1 receptor antagonist or other cytokines in the acute therapeutic effects of IVIg?","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; University of Toronto; St. Michael's Hospital","funders":"","keywords":"Receptor antagonist; Immunology; Receptor; Medicine; Mechanism of action; Interleukin; Immune system; Interleukin 1 receptor antagonist; Proinflammatory cytokine; Cytokine; Biology; Antagonist; Inflammation; In vitro; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005636331,0.0001004296,0.0002212986,0.0000378355,0.00003086443,0.000007995881,0.00006309994,0.00004736444,0.00001658768],"category_scores_gemma":[0.00001124262,0.0000525479,0.00006938761,0.0001128536,0.00002916721,0.00002089108,0.000005874052,0.00004091737,0.000007366923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006663871,"about_ca_system_score_gemma":0.00002694845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001388838,"about_ca_topic_score_gemma":0.0001174076,"domain_scores_codex":[0.9994799,0.00002133047,0.0001280129,0.0001183898,0.00009695082,0.0001553866],"domain_scores_gemma":[0.9996433,0.0001241019,0.00004582071,0.0001542172,0.00001778368,0.00001482298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004160239,0.02461722,0.1726832,0.0010972,0.002707335,0.0008379194,0.002321175,0.000002424877,0.7636112,0.001600872,0.004020128,0.02234104],"study_design_scores_gemma":[0.07089937,0.005871017,0.162084,0.0005001158,0.003448256,0.0004054107,0.0004746624,0.00007755345,0.6924275,0.00414529,0.05916537,0.0005014908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968022,0.0008282628,0.00001681672,0.0004146886,0.00003288577,0.0008128119,0.00004802226,0.00001536977,0.001028976],"genre_scores_gemma":[0.9984363,0.00004784267,0.0002836951,0.0003697498,0.00006198571,0.0001349454,0.00002959774,0.00001803802,0.0006178094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07118373,"threshold_uncertainty_score":0.2142841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00831932442796028,"score_gpt":0.2572748859433157,"score_spread":0.2489555615153554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}