{"id":"W2125054984","doi":"10.1093/hmg/ddp446","title":"Identification of a microRNA signature associated with progression of leukoplakia to oral carcinoma","year":2009,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":265,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Public Health Ontario; Hospital for Sick Children; Toronto General Hospital; University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Biology; microRNA; Oral leukoplakia; Cancer; Malignant transformation; Pathology; Tumor progression; Leukoplakia; Carcinoma; Cancer research; Medicine; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001707614,0.0001529772,0.0002636678,0.0007147528,0.0002135976,0.0004430395,0.0001072267,0.0001990274,0.0009060468],"category_scores_gemma":[0.0005475547,0.0001777562,0.0001814918,0.0004575187,0.0001758445,0.0001251191,0.0002086593,0.0002503113,0.0002472091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001776714,"about_ca_system_score_gemma":0.0001766176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006839832,"about_ca_topic_score_gemma":0.0008832129,"domain_scores_codex":[0.999856,0.00001626096,0.00001885111,0.00004651588,0.00003453433,0.00002781232],"domain_scores_gemma":[0.9997253,0.00005588393,0.0001136816,0.00002492179,0.00004234766,0.00003784442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001559385,0.00008414048,0.4064044,0.0001173093,0.00006509895,0.001029556,0.0003733489,0.0002193934,0.573108,0.0001091113,0.0001679671,0.01676231],"study_design_scores_gemma":[0.00001517665,0.0002644944,0.9673029,0.000005657499,0.00005340848,0.002256868,0.0001420912,0.0004756148,0.02858482,0.00006655075,0.0008241683,0.000008358427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998884,0.0002614829,0.0003767085,0.00001094081,0.000002112357,0.00001258878,0.0001600839,0.00001543119,0.0002765579],"genre_scores_gemma":[0.9982894,0.0001621897,0.0007115629,0.00001471466,0.00000353766,0.00001454095,0.0004793664,0.000006437162,0.0003182757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009060468,"threshold_uncertainty_score":0.003031015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009981588908687456,"score_gpt":0.2936550364292446,"score_spread":0.2836734475205571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}