{"id":"W2125054984","doi":"10.1093/hmg/ddp446","title":"Identification of a microRNA signature associated with progression of leukoplakia to oral carcinoma","year":2009,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":265,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Public Health Ontario; Hospital for Sick Children; Toronto General Hospital; University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Biology; microRNA; Oral leukoplakia; Cancer; Malignant transformation; Pathology; Tumor progression; Leukoplakia; Carcinoma; Cancer research; Medicine; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000231525,0.0002106822,0.0002455284,0.0001511776,0.00005958581,0.00001989393,0.0003567517,0.0002725155,0.00001011276],"category_scores_gemma":[0.00007787265,0.0002080697,0.0001111944,0.0003440342,0.00008863614,0.000002719618,0.00009757184,0.0001592269,0.000001989975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003809498,"about_ca_system_score_gemma":0.0001435763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005828836,"about_ca_topic_score_gemma":0.00002495538,"domain_scores_codex":[0.998255,0.0001202558,0.0004045523,0.0004370721,0.0004722145,0.0003108941],"domain_scores_gemma":[0.9985218,0.000004184296,0.0002610648,0.0006194614,0.0004685775,0.0001249251],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001363301,0.0001643181,0.0001249927,0.00002028999,0.00007405672,0.00001653395,0.00007036894,0.001121212,0.9961422,0.0001278397,0.0002391372,0.00176272],"study_design_scores_gemma":[0.0007964359,0.002227675,0.01077786,0.00006995704,0.00005861063,0.000007969365,0.00002124743,0.0001092222,0.9853271,0.0001364716,0.0002458711,0.0002216417],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9752594,0.001106916,0.02274722,0.00006024624,0.00003090393,0.0005926302,0.00003018051,0.00001131813,0.0001612512],"genre_scores_gemma":[0.998035,0.00001853095,0.001433468,0.0001173537,0.00002543662,0.00001773034,0.0001923544,0.00004150896,0.0001186755],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02277561,"threshold_uncertainty_score":0.8484834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009981588908687456,"score_gpt":0.2936550364292446,"score_spread":0.2836734475205571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}