{"id":"W2125153455","doi":"10.1111/j.1365-2958.2008.06519.x","title":"The histone methylase KMTox interacts with the redox‐sensor peroxiredoxin‐1 and targets genes involved in <i>Toxoplasma gondii</i> antioxidant defences","year":2008,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôtel-Dieu de Québec","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Centre National de la Recherche Scientifique; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; University of Glasgow; Wellcome Trust","keywords":"Biology; Peroxiredoxin; Cell biology; Toxoplasma gondii; Histone; Chromatin; Oxidative stress; Thioredoxin; Intracellular parasite; Intracellular; Biochemistry; Gene; Genetics; Enzyme; Peroxidase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001133879,0.0001945798,0.0001301576,0.00007480056,0.000144185,0.000153595,0.0001092132,0.0002302038,0.001186411],"category_scores_gemma":[0.0001218188,0.0001210934,0.0001563976,0.00007091025,0.0001362945,0.0001674709,0.0002080114,0.0002233882,0.0003799199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001538013,"about_ca_system_score_gemma":0.00008263589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003590998,"about_ca_topic_score_gemma":0.0006060526,"domain_scores_codex":[0.9999315,0.00001240528,0.00000281959,0.00001858974,0.00001758448,0.00001709334],"domain_scores_gemma":[0.9999317,0.0000140258,0.00002150829,0.000007663724,0.000009156938,0.00001594165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003997868,0.000009154644,0.001525629,0.00002248584,0.000004696749,0.00005895025,0.00001874034,0.00002347866,0.9972007,0.00005939425,0.00002011882,0.001016651],"study_design_scores_gemma":[0.00001371523,0.0002149517,0.04434914,0.00001026362,0.00001881788,0.0008798433,0.00009478819,0.0009234146,0.9498802,0.0001235895,0.003485563,0.000005687904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958192,0.001138151,0.002094102,0.00006531251,0.00001121919,0.000006267194,0.00003609745,0.00001626726,0.0008132639],"genre_scores_gemma":[0.9954074,0.0004334466,0.001844366,0.00003654952,0.000007711988,0.000004975318,0.0001997542,0.000006367346,0.002059504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001186411,"threshold_uncertainty_score":0.003968894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009711507385970366,"score_gpt":0.2378254094577231,"score_spread":0.2281139020717527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}