{"id":"W2125153455","doi":"10.1111/j.1365-2958.2008.06519.x","title":"The histone methylase KMTox interacts with the redox‐sensor peroxiredoxin‐1 and targets genes involved in <i>Toxoplasma gondii</i> antioxidant defences","year":2008,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôtel-Dieu de Québec","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Centre National de la Recherche Scientifique; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; University of Glasgow; Wellcome Trust","keywords":"Biology; Peroxiredoxin; Cell biology; Toxoplasma gondii; Histone; Chromatin; Oxidative stress; Thioredoxin; Intracellular parasite; Intracellular; Biochemistry; Gene; Genetics; Enzyme; Peroxidase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0006189,0.0004465215,0.0005677443,0.0001857983,0.001023084,0.00003217406,0.0006161083,0.0003091663,0.00003267314],"category_scores_gemma":[0.000273274,0.0002411916,0.0001174659,0.0003286546,0.003785411,0.00008282338,0.0004599324,0.000799881,0.0001166885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008818445,"about_ca_system_score_gemma":0.0001393956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002259388,"about_ca_topic_score_gemma":0.001457115,"domain_scores_codex":[0.9965383,0.001222265,0.0004532143,0.0007142021,0.0000573504,0.001014651],"domain_scores_gemma":[0.9981515,0.0008662898,0.0002127622,0.000572594,0.0001466132,0.00005020439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004545266,0.0000938338,0.002115512,0.00001520575,0.0003235413,0.0003521618,0.001147426,0.00001287128,0.9909512,0.0001991255,0.003583525,0.0007510888],"study_design_scores_gemma":[0.001921319,0.0005692689,0.003437275,0.00003876192,0.00004954918,0.001795732,0.001418609,0.000003896278,0.7993667,0.00004748825,0.1909279,0.0004234911],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9411262,0.05337486,0.00008684552,0.00406839,0.0003633978,0.0006381397,0.00005903225,0.00005954186,0.0002235659],"genre_scores_gemma":[0.9935448,0.003592886,0.0003553443,0.0006277938,0.00002187581,0.0001383274,0.00006604276,0.00003985979,0.001613083],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1915845,"threshold_uncertainty_score":0.9989257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009711507385970366,"score_gpt":0.2378254094577231,"score_spread":0.2281139020717527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}