{"id":"W2125160258","doi":"10.2174/157016207780077066","title":"Synergistic Effect of Combined HIV/HCV Immunogens: A Combined HIV-1/HCV Candidate Vaccine Induces a Higher Level of CD8+ T Cell-Immune Responses in HLA-A2.1 Mice","year":2007,"lang":"en","type":"article","venue":"Current HIV Research","topic":"Hepatitis C virus research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Children's Hospital of Eastern Ontario","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"ELISPOT; HIV vaccine; Virology; Hepatitis C virus; Immune system; Immunology; CD8; Medicine; Vaccination; Virus; Vaccine trial","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.01087489,0.0005858459,0.001787832,0.003007627,0.0002216232,0.00005504248,0.001132728,0.0003602543,0.0008478701],"category_scores_gemma":[0.004581662,0.0005067962,0.0003159557,0.003400141,0.000719203,0.0001907485,0.0008423236,0.002450031,0.0004276014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007125506,"about_ca_system_score_gemma":0.001049089,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002124433,"about_ca_topic_score_gemma":0.0002579847,"domain_scores_codex":[0.9894668,0.002628913,0.001921012,0.0009397781,0.003061269,0.001982246],"domain_scores_gemma":[0.9905061,0.005594455,0.000371052,0.001591378,0.001359795,0.0005772288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03573471,0.002868525,0.1739797,0.004828048,0.0003318397,0.000644032,0.001190395,0.000008893157,0.7526584,0.0002444482,0.01016374,0.0173472],"study_design_scores_gemma":[0.03112418,0.006020445,0.3202048,0.003928848,0.0001653135,0.00001110106,0.000344863,0.0005832651,0.6258159,0.00008327983,0.01096612,0.0007518487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867631,0.005765501,0.0000818252,0.0008954126,0.000370838,0.002704608,0.0004967038,0.00006122621,0.002860841],"genre_scores_gemma":[0.9919766,0.001124655,0.0001009087,0.00001475866,0.00013646,0.0002032702,0.0004599989,0.0001254286,0.005857901],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1462251,"threshold_uncertainty_score":0.9998513,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1369407193558327,"score_gpt":0.424503840478159,"score_spread":0.2875631211223263,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}