{"id":"W2125178051","doi":"10.1085/jgp.201511361","title":"CaV1.2/CaV3.x channels mediate divergent vasomotor responses in human cerebral arteries","year":2015,"lang":"en","type":"article","venue":"The Journal of General Physiology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Innovates - Health Solutions","keywords":"Cerebral arteries; Cerebral circulation; Electrical impedance myography; Cerebral blood flow; Vascular smooth muscle; Biology; Internal medicine; Anatomy; Medicine; Endocrinology; Smooth muscle; Vasodilation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005029562,0.0001105112,0.000173544,0.00007605654,0.00006560297,0.000008054295,0.0001871285,0.00009380778,0.00003143579],"category_scores_gemma":[0.00009278054,0.0000726211,0.00007687694,0.0000672297,0.0001052006,0.000008519393,0.00008145395,0.0001135651,0.000006191548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002667528,"about_ca_system_score_gemma":0.00008207253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002877297,"about_ca_topic_score_gemma":0.00001950723,"domain_scores_codex":[0.9989501,0.0003444871,0.0002959988,0.000102372,0.0001306067,0.0001765005],"domain_scores_gemma":[0.9993219,0.00001375594,0.0002659425,0.0001545715,0.0001587851,0.0000850436],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001148208,0.000049272,0.0005353675,0.000003122064,0.0000351494,0.000002775268,0.0003789803,0.004615999,0.9830941,0.00006921514,0.009921701,0.000146089],"study_design_scores_gemma":[0.006727462,0.0061092,0.1213309,0.00003953673,0.00008664744,0.000371852,0.001335188,0.001322217,0.7882071,0.008353621,0.06545606,0.0006602703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997309,0.0002752072,0.0001465991,0.0005506627,0.001563506,0.00006913402,0.00000422541,0.000003107072,0.00007854771],"genre_scores_gemma":[0.9961437,0.0000877377,0.00004854756,0.0003558238,0.002227604,0.000002733098,0.00002168959,0.00001091686,0.001101238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1948871,"threshold_uncertainty_score":0.2961403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03061527057330854,"score_gpt":0.276768493938724,"score_spread":0.2461532233654155,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}