{"id":"W2125212638","doi":"10.1016/s0378-1119(00)00280-8","title":"The KLK7 (PRSS6) gene, encoding for the stratum corneum chymotryptic enzyme is a new member of the human kallikrein gene family — genomic characterization, mapping, tissue expression and hormonal regulation","year":2000,"lang":"en","type":"article","venue":"Gene","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Biology; Gene; Gene family; Kallikrein; Complementary DNA; Pair-rule gene; Genetics; Exon; Locus (genetics); Molecular biology; Genomic organization; Structural gene; Coding region; Intron; Gene expression; Regulator gene; Genome; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001107133,0.0003548581,0.0002641477,0.000516468,0.0001994511,0.0004766865,0.0001819834,0.0004024649,0.001197096],"category_scores_gemma":[0.0002165108,0.00012954,0.0003523818,0.0002563027,0.0002995532,0.0002400542,0.0002670382,0.0005596712,0.0008975852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002338173,"about_ca_system_score_gemma":0.0002123291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004163784,"about_ca_topic_score_gemma":0.0004469184,"domain_scores_codex":[0.999862,0.00001368179,0.000009338219,0.00003273096,0.00005629524,0.00002610266],"domain_scores_gemma":[0.9998099,0.00003400429,0.00004906725,0.00001629724,0.00003426383,0.00005644832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002013437,0.00002367927,0.001527079,0.00003914275,0.00001180528,0.0008131589,0.00003111561,0.00007054812,0.9899147,0.0003108087,0.0001754206,0.006881271],"study_design_scores_gemma":[0.00009297419,0.0007967668,0.08053163,0.00003508908,0.00009606256,0.01728302,0.0001984772,0.002000799,0.8666745,0.001232961,0.03101783,0.00003991147],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9779994,0.006335734,0.01035307,0.0005542196,0.0001697505,0.00003968801,0.001616702,0.0002961715,0.002635321],"genre_scores_gemma":[0.9744142,0.003234831,0.007442305,0.0001691061,0.00006666673,0.00002350919,0.005030162,0.00004238358,0.009576901],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001197096,"threshold_uncertainty_score":0.004004717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02822064279057202,"score_gpt":0.2559173550539935,"score_spread":0.2276967122634215,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}