{"id":"W2125244981","doi":"10.1128/ec.00305-10","title":"Conjugated Linoleic Acid Inhibits Hyphal Growth in Candida albicans by Modulating Ras1p Cellular Levels and Downregulating TEC1 Expression","year":2011,"lang":"en","type":"article","venue":"Eukaryotic Cell","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Biotechnology Research Institute; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; University of California, Irvine; Fonds Québécois de la Recherche sur la Nature et les Technologies; Carnegie Mellon University","keywords":"Candida albicans; Hypha; Biology; Conjugated linoleic acid; Cell biology; Downregulation and upregulation; Yeast; Corpus albicans; Growth inhibition; Gene expression; Microbiology; Cell growth; Linoleic acid; Biochemistry; Gene; Fatty acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008248386,0.0003508613,0.0002350937,0.0001996872,0.0001252848,0.0002464743,0.0001710779,0.000211608,0.0006895793],"category_scores_gemma":[0.00008016112,0.00008968883,0.0002004694,0.0001500231,0.0001456476,0.0001021991,0.0001416602,0.0004720751,0.0002220055],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002007094,"about_ca_system_score_gemma":0.0002200914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000622847,"about_ca_topic_score_gemma":0.001058175,"domain_scores_codex":[0.9998822,0.00001925768,0.00001243412,0.00001936006,0.00003506289,0.00003168366],"domain_scores_gemma":[0.9999489,0.000009123214,0.00001238428,0.0000070911,0.000009302152,0.00001323739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009599321,0.00001940353,0.00004299175,0.0000225002,0.000002184332,0.00001404659,0.000004683315,0.00003121423,0.9990221,0.00002160052,0.0000125773,0.0007107178],"study_design_scores_gemma":[0.000007594737,0.0001654229,0.001399211,0.00000283784,0.000006830737,0.00003558215,0.000009732826,0.0003548901,0.9973632,0.00001163629,0.0006413161,0.000001848471],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945603,0.002407909,0.001177872,0.00009197089,0.00002363252,0.00001995622,0.0003904667,0.0000677361,0.001260167],"genre_scores_gemma":[0.9936557,0.001605974,0.001790743,0.00005503251,0.00001178002,0.00003667585,0.0005344306,0.00001763967,0.00229201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006895793,"threshold_uncertainty_score":0.002306819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02286249140855464,"score_gpt":0.2265947442337551,"score_spread":0.2037322528252005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}