{"id":"W2125288626","doi":"10.1586/erv.10.162","title":"Hepatitis B surface antigen-1018 ISS adjuvant-containing vaccine: a review of HEPLISAV™ safety and efficacy","year":2011,"lang":"en","type":"review","venue":"Expert Review of Vaccines","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Immunogenicity; Adjuvant; Medicine; Immunization; Immune system; Immunology; Antigen; Virology; Vaccination; Hepatitis B virus; Hepatitis B vaccine; Hepatitis B; Virus; HBsAg","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008537808,0.0007362858,0.001623345,0.002232386,0.0001668913,0.0006936768,0.0006786298,0.0006969934,0.002709401],"category_scores_gemma":[0.001024464,0.0002851618,0.0007009699,0.002222694,0.0002849216,0.0008501094,0.0003600777,0.0007626917,0.001006224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004653907,"about_ca_system_score_gemma":0.001118579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001025244,"about_ca_topic_score_gemma":0.001601795,"domain_scores_codex":[0.9997661,0.00005564811,0.00005634748,0.0000321254,0.00007628438,0.00001350104],"domain_scores_gemma":[0.9995177,0.0002741826,0.00008547777,0.000008994697,0.00009529134,0.0000183861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001485252,0.00007176349,0.0001952161,0.06935585,0.0002249214,0.0001452965,0.00004946199,0.0001987809,0.00198721,0.001264762,0.01232117,0.914037],"study_design_scores_gemma":[0.00007497451,0.000450805,0.001993524,0.02882588,0.001107274,0.001823958,0.0001291054,0.0001151899,0.001801195,0.001287114,0.9623523,0.00003869145],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009650431,0.9995006,0.00003326129,0.00007513678,0.00003716346,0.000003842443,0.00001124365,0.000001581761,0.0002406361],"genre_scores_gemma":[0.0004935837,0.9991869,0.0001014103,0.0000591101,0.00003227083,0.000004879858,0.0000140279,4.743568e-7,0.0001073238],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002709401,"threshold_uncertainty_score":0.00906378,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04528607836130995,"score_gpt":0.3732709874222741,"score_spread":0.3279849090609642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}