{"id":"W2125346129","doi":"10.1530/erc-13-0293","title":"TBLR1 as an androgen receptor (AR) coactivator selectively activates AR target genes to inhibit prostate cancer growth","year":2013,"lang":"en","type":"article","venue":"Endocrine Related Cancer","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"York University; National Cancer Institute; National Institutes of Health; DOD Prostate Cancer Research Program; National Center for Research Resources; Office of Research and Development; U.S. Department of Veterans Affairs; U.S. Department of Defense","keywords":"Coactivator; Androgen receptor; Prostate cancer; Cancer research; Corepressor; Nuclear receptor coactivator 3; Nuclear receptor; Endocrinology; Androgen; Biology; Ectopic expression; LNCaP; Internal medicine; Cell growth; Prostate; Cancer; Chemistry; Cell biology; Medicine; Cell culture; Hormone; Gene; Transcription factor; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000127862,0.000274744,0.0002860184,0.0001781748,0.0002209802,0.0002862408,0.0002588676,0.0001958558,0.002381842],"category_scores_gemma":[0.00006541914,0.0001457209,0.0003865919,0.0002303272,0.000209123,0.0001491041,0.0002110355,0.0006674404,0.0009818638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003422496,"about_ca_system_score_gemma":0.0002082322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006374266,"about_ca_topic_score_gemma":0.001318046,"domain_scores_codex":[0.9998158,0.00002448542,0.00001035284,0.00004887306,0.00005784282,0.00004275373],"domain_scores_gemma":[0.9999551,0.000004634423,0.00001248084,0.000004972854,0.000005615337,0.00001719985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000469859,0.00001519707,0.0001622311,0.00004602709,0.000004885069,0.00001929199,0.000009090149,0.00005127094,0.9977472,0.00007987542,0.0001208112,0.001697085],"study_design_scores_gemma":[0.00001989059,0.0002805027,0.003510057,0.000007706961,0.00002522281,0.0003274749,0.00002415251,0.0006967119,0.9859287,0.0000305568,0.009143663,0.000005286399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9616708,0.019106,0.01037047,0.0004489291,0.0001837269,0.00006322639,0.0009164374,0.0005677821,0.00667258],"genre_scores_gemma":[0.984435,0.003510132,0.003812597,0.0001388378,0.00002594535,0.00005181634,0.001127027,0.00005307903,0.00684549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002381842,"threshold_uncertainty_score":0.007968009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01300043707993847,"score_gpt":0.3116068075852786,"score_spread":0.2986063705053402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}