{"id":"W2125346129","doi":"10.1530/erc-13-0293","title":"TBLR1 as an androgen receptor (AR) coactivator selectively activates AR target genes to inhibit prostate cancer growth","year":2013,"lang":"en","type":"article","venue":"Endocrine Related Cancer","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"York University; National Cancer Institute; National Institutes of Health; DOD Prostate Cancer Research Program; National Center for Research Resources; Office of Research and Development; U.S. Department of Veterans Affairs; U.S. Department of Defense","keywords":"Coactivator; Androgen receptor; Prostate cancer; Cancer research; Corepressor; Nuclear receptor coactivator 3; Nuclear receptor; Endocrinology; Androgen; Biology; Ectopic expression; LNCaP; Internal medicine; Cell growth; Prostate; Cancer; Chemistry; Cell biology; Medicine; Cell culture; Hormone; Gene; Transcription factor; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000110306,0.0005429898,0.0006971547,0.0003416144,0.0002710337,0.0001009263,0.0002257221,0.0001654516,0.007697391],"category_scores_gemma":[0.00009411474,0.0004155168,0.0001541074,0.001237373,0.0001425534,0.00069914,0.0001278968,0.000673678,0.0006785498],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001152765,"about_ca_system_score_gemma":0.0009962262,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01019339,"about_ca_topic_score_gemma":0.00008777539,"domain_scores_codex":[0.9965843,0.000130998,0.0004780728,0.0009599702,0.0006542283,0.001192424],"domain_scores_gemma":[0.9976504,0.00006987555,0.0001624053,0.0004166581,0.0007744928,0.0009261746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003945618,0.0009318248,0.2163117,0.0003145396,0.002569787,0.0002811092,0.002801893,0.0001296176,0.6705933,0.0001800004,0.05014879,0.05179184],"study_design_scores_gemma":[0.004997079,0.00124512,0.0107081,0.0003476569,0.0001599606,0.000077085,0.0003320302,0.00009647363,0.9188784,0.000508897,0.06204981,0.0005993352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9751478,0.008160414,0.000004123574,0.01077778,0.0004045923,0.00305046,0.0001862056,0.0003246159,0.00194399],"genre_scores_gemma":[0.9531387,0.01055351,0.0006537925,0.0009064719,0.0005884624,0.00409773,0.0002577448,0.0002098998,0.02959365],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2482852,"threshold_uncertainty_score":0.9998296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01300043707993847,"score_gpt":0.3116068075852786,"score_spread":0.2986063705053402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}