{"id":"W2125355741","doi":"10.1016/j.jalz.2014.05.710","title":"P2‐037: THE QUEST FOR EARLY REVERSIBLE CHANGES IN ALZHEIMER'S DISEASE: MASS SPECTROMETRIC IMAGING OF GANGLIOSIDES IN A NOVEL TRANSGENIC RAT MODEL OF PRODROMAL AD","year":2014,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Ganglioside; Biology; Disease; Genetically modified mouse; Cell biology; Neuroscience; Cell; Alzheimer's disease; Transgene; Medicine; Biochemistry; Pathology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007061989,0.001245869,0.0006465575,0.001161012,0.0005207867,0.0005727605,0.0008635494,0.001640195,0.002389373],"category_scores_gemma":[0.0002013669,0.0004571059,0.0006449263,0.0003432864,0.0008130841,0.001094325,0.0003078643,0.002044589,0.001175858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007674189,"about_ca_system_score_gemma":0.0006555817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00320843,"about_ca_topic_score_gemma":0.00331114,"domain_scores_codex":[0.9997262,0.000035277,0.00002175229,0.0000798927,0.00006413965,0.0000727009],"domain_scores_gemma":[0.9997399,0.00001835911,0.00005300511,0.0000259187,0.00007149507,0.00009121713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004012479,0.0001989853,0.0001302933,0.00004298315,0.00001141253,0.0001639877,0.00003151851,0.00003307086,0.9970322,0.000242075,0.0002164607,0.001495703],"study_design_scores_gemma":[0.000234182,0.002673321,0.003801103,0.00002595417,0.0000922773,0.001377699,0.000138104,0.002152971,0.9836304,0.0004585029,0.005385369,0.00003018314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9656965,0.00334536,0.02137539,0.002459478,0.0003896008,0.0002696867,0.001603365,0.0009440833,0.003916466],"genre_scores_gemma":[0.9386305,0.003937208,0.03308689,0.0008661069,0.0001331429,0.0005820231,0.002002775,0.0003407187,0.02042071],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00320843,"threshold_uncertainty_score":0.007993221,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03764200313049745,"score_gpt":0.2947908169373666,"score_spread":0.2571488138068692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}