{"id":"W2125415514","doi":"10.1074/jbc.m709221200","title":"Steroidogenic Activity of StAR Requires Contact with Mitochondrial VDAC1 and Phosphate Carrier Protein","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":139,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; March of Dimes Foundation; National Institutes of Health; Pfizer; American Heart Association; Howard Hughes Medical Institute","keywords":"VDAC1; Steroidogenic acute regulatory protein; Cholesterol side-chain cleavage enzyme; Inner mitochondrial membrane; Cell biology; Phosphorylation; Biology; Chemistry; Mitochondrion; Biochemistry; Gene expression; Bacterial outer membrane; Cytochrome P450","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001608604,0.0001983084,0.0002408694,0.0001414109,0.0003349776,0.0003851092,0.0001623974,0.000230757,0.001898701],"category_scores_gemma":[0.000205407,0.0001360519,0.0002340097,0.0001027888,0.0002502784,0.000329488,0.0003065609,0.0003803295,0.0006988485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004771923,"about_ca_system_score_gemma":0.0003352814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008234418,"about_ca_topic_score_gemma":0.001023981,"domain_scores_codex":[0.9998209,0.00002353521,0.00001020747,0.00004271491,0.00005561927,0.00004703329],"domain_scores_gemma":[0.9998102,0.00002837245,0.00004300465,0.00002675506,0.00003406724,0.00005767631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000142733,0.00001589458,0.0005476032,0.0000332967,0.00000432133,0.0001406945,0.00003032664,0.00003302618,0.9971493,0.0004507535,0.00006433009,0.001387776],"study_design_scores_gemma":[0.00002502071,0.0001603228,0.02014572,0.000007285025,0.00000937409,0.001553613,0.00008824929,0.001100977,0.9702241,0.0003893704,0.006287066,0.000008987299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904512,0.003009649,0.003455169,0.0002942487,0.00005589184,0.00001725284,0.000143955,0.00005852194,0.002514236],"genre_scores_gemma":[0.9939702,0.0009104152,0.001549186,0.00004329238,0.00001605133,0.000009867611,0.0004090614,0.00001060947,0.003081345],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001898701,"threshold_uncertainty_score":0.006351829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02107656150934727,"score_gpt":0.23623080008675,"score_spread":0.2151542385774028,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}