{"id":"W2125421419","doi":"10.1080/13880200490505474","title":"Isolation and Characterization of Compounds with Anti-prostate Cancer Activity from<i>Arctium lappa</i>L. Using Bioactivity-guided Fractionation","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Biology","topic":"Plant-derived Lignans Synthesis and Bioactivity","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; University of British Columbia","keywords":"Arctium lappa; LNCaP; Fractionation; Chemistry; Prostate cancer; Traditional medicine; Cytotoxicity; Cancer cell lines; Cancer; Chromatography; Medicine; Cancer cell; Biochemistry; In vitro; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001374129,0.0001778664,0.0002389214,0.00005829814,0.0001079449,0.00001594405,0.00006616727,0.0001842658,0.00001401578],"category_scores_gemma":[0.00001974719,0.0001492103,0.00003910256,0.0001027281,0.0002423988,0.00003096276,0.0000574006,0.0001264227,9.230179e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004005774,"about_ca_system_score_gemma":0.0000881618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004557087,"about_ca_topic_score_gemma":0.00004324358,"domain_scores_codex":[0.998998,0.0001338961,0.0001755084,0.0003910513,0.00008911302,0.0002124641],"domain_scores_gemma":[0.9994614,0.00004188299,0.0001956145,0.0001295506,0.00009431369,0.00007722049],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003988279,0.0001580786,0.03920554,0.00001839905,0.0001055508,7.832314e-7,0.00002662555,0.00004470248,0.9569002,0.00004859194,0.000001743331,0.003091007],"study_design_scores_gemma":[0.0009113254,0.0001239633,0.08073694,0.00002132099,0.00006662401,0.00001446338,0.00001103077,0.0009059581,0.9161543,0.00006288287,0.000807825,0.0001833597],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852758,0.00009598499,0.01330741,0.0005284075,0.0001338109,0.000211119,0.0003885482,0.00001537568,0.00004355938],"genre_scores_gemma":[0.9979511,0.0006117946,0.0007855991,0.0001542012,0.0001495721,0.000013929,0.0003150117,0.00001518704,0.000003581041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04153141,"threshold_uncertainty_score":0.6084622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03590570508202822,"score_gpt":0.3214845804034991,"score_spread":0.2855788753214709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}