{"id":"W2125421419","doi":"10.1080/13880200490505474","title":"Isolation and Characterization of Compounds with Anti-prostate Cancer Activity from<i>Arctium lappa</i>L. Using Bioactivity-guided Fractionation","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Biology","topic":"Plant-derived Lignans Synthesis and Bioactivity","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; University of British Columbia","keywords":"Arctium lappa; LNCaP; Fractionation; Chemistry; Prostate cancer; Traditional medicine; Cytotoxicity; Cancer cell lines; Cancer; Chromatography; Medicine; Cancer cell; Biochemistry; In vitro; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007466316,0.00053286,0.0002945519,0.0006082084,0.0001500317,0.0001977237,0.0002142543,0.0002260819,0.001523953],"category_scores_gemma":[0.0001752325,0.0001243603,0.0003538966,0.0004914885,0.0001679753,0.0002275785,0.0001108173,0.0004682259,0.0004510085],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001298059,"about_ca_system_score_gemma":0.0002373187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007061879,"about_ca_topic_score_gemma":0.0007284751,"domain_scores_codex":[0.9999667,0.000004962968,0.000003306809,0.000007508709,0.000008423161,0.000009016313],"domain_scores_gemma":[0.9999037,0.00001760748,0.0000246218,0.000008849243,0.00002059397,0.00002459246],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001827913,0.00006106473,0.0002520094,0.0001399692,0.00001335377,0.0002284774,0.00001745735,0.0001121944,0.9910662,0.00004677474,0.00005222296,0.007827538],"study_design_scores_gemma":[0.0001063061,0.001526167,0.01204558,0.0000243121,0.0001106944,0.001929825,0.00004632611,0.0003395099,0.975465,0.0001056886,0.008282497,0.00001808572],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9769177,0.008363318,0.006785208,0.0003055461,0.00003432042,0.0002030378,0.001694304,0.0001554929,0.005540905],"genre_scores_gemma":[0.9742002,0.005739164,0.01015362,0.00033206,0.00007286838,0.00009753825,0.005040105,0.00004022823,0.004324193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001523953,"threshold_uncertainty_score":0.005098104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03590570508202822,"score_gpt":0.3214845804034991,"score_spread":0.2855788753214709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}