{"id":"W2125427036","doi":"10.1016/j.tetlet.2009.12.086","title":"A bifunctional chelator featuring the DOTAM-Gly-l-Phe-OH structural subunit: en route toward homo- and heterobimetallic lanthanide(III) complexes as PARACEST MRI contrast agents","year":2009,"lang":"en","type":"article","venue":"Tetrahedron Letters","topic":"Lanthanide and Transition Metal Complexes","field":"Materials Science","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Bifunctional; Chemistry; Chelation; Lanthanide; Molecule; Stereochemistry; Combinatorial chemistry; Crystallography; Inorganic chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003264097,0.0004151104,0.0004509308,0.0001184449,0.0005029088,0.0004204602,0.0004533126,0.00009150933,0.000744921],"category_scores_gemma":[0.00002532229,0.0002924314,0.0001463477,0.0002283571,0.0002917081,0.0005827743,0.00006915978,0.0003251508,0.0001853436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007856054,"about_ca_system_score_gemma":0.00003212571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004179137,"about_ca_topic_score_gemma":0.0000739916,"domain_scores_codex":[0.9975939,0.0002305071,0.0004273345,0.0005787255,0.0005509969,0.0006185371],"domain_scores_gemma":[0.9990417,0.0001966664,0.0001591187,0.0003611805,0.0000548532,0.0001864735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002146242,0.00004746535,0.001713992,0.00003654887,0.00008825502,0.0001142071,0.001070591,0.0002186966,0.9935156,0.00166142,0.0008975726,0.000421068],"study_design_scores_gemma":[0.005298454,0.0006977742,0.6355966,0.0001935246,0.0004448222,0.002173661,0.0007282982,0.0008662583,0.3415697,0.00278633,0.007782695,0.001861928],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902885,0.00024622,0.0004810616,0.007472732,0.0005527645,0.0004175486,0.0001426339,0.0002042672,0.0001942653],"genre_scores_gemma":[0.9942371,0.00003699845,0.0006100454,0.004493647,0.0003317891,0.00001330651,0.00009735782,0.00002848346,0.0001512293],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6519459,"threshold_uncertainty_score":0.9999528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01531610821550715,"score_gpt":0.2485122712152321,"score_spread":0.233196162999725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}