{"id":"W2125428954","doi":"10.1002/cbic.200700266","title":"Strong Inhibition of Cholera Toxin by Multivalent GM1 Derivatives","year":2007,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":109,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Cholera toxin; Toxin; Chemistry; Ligand (biochemistry); Derivative (finance); Stereochemistry; Combinatorial chemistry; Oligosaccharide; Vibrio cholerae; Biophysics; Biochemistry; Microbiology; Biology; Receptor; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002028364,0.0003842046,0.0003063412,0.0001358238,0.00009289021,0.0002442913,0.0002240395,0.0002355516,0.0006784016],"category_scores_gemma":[0.000173853,0.0001261574,0.0001619497,0.0001088014,0.0002712844,0.0001334212,0.0003371226,0.0004617518,0.0002141806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004052576,"about_ca_system_score_gemma":0.000192198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006297046,"about_ca_topic_score_gemma":0.001008899,"domain_scores_codex":[0.999823,0.00002144294,0.000009869101,0.00003665369,0.00006257877,0.00004647932],"domain_scores_gemma":[0.9998971,0.0000298821,0.00002146155,0.000009783149,0.00001113883,0.00003070981],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002783383,0.000004941193,0.00002216826,0.00001428562,0.000002223864,0.00001228518,0.000005685798,0.00006000291,0.9994742,0.00005155869,0.00001546796,0.0003092574],"study_design_scores_gemma":[0.000006608553,0.00008014669,0.0002891155,0.000002186126,0.000003466038,0.00004855277,0.000002592094,0.000423773,0.9986573,0.00001354855,0.0004705283,0.000002060469],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938018,0.001183118,0.003130361,0.00005516052,0.00002211123,0.00002332489,0.0001354777,0.00006932073,0.001579345],"genre_scores_gemma":[0.9964222,0.0003642603,0.001700152,0.00004618334,0.000005732191,0.00001878499,0.0001234985,0.00001538559,0.001303915],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006784016,"threshold_uncertainty_score":0.002940297,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02783969089947008,"score_gpt":0.3305733577141642,"score_spread":0.3027336668146941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}