{"id":"W2125620887","doi":"10.1016/s1470-2045(11)70033-x","title":"Treatment with trastuzumab for 1 year after adjuvant chemotherapy in patients with HER2-positive early breast cancer: a 4-year follow-up of a randomised controlled trial","year":2011,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":611,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Trastuzumab; Medicine; Internal medicine; Interim analysis; Breast cancer; Oncology; Clinical endpoint; Population; Adjuvant; Surgery; Clinical trial; Hazard ratio; Cancer; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004283765,0.0002167294,0.001456706,0.00008817028,0.00003144454,0.000005919117,0.0001516019,0.0001174921,0.0003424112],"category_scores_gemma":[0.00002428061,0.0001069383,0.0001395663,0.0001612541,0.0002358686,0.00003481175,0.00001457848,0.0001850021,0.000005137856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006335611,"about_ca_system_score_gemma":0.000791151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001222638,"about_ca_topic_score_gemma":0.001130158,"domain_scores_codex":[0.9983104,0.000286045,0.000343727,0.0002944505,0.0002965003,0.0004688609],"domain_scores_gemma":[0.9988332,0.0002947705,0.0001903247,0.0003493215,0.0002359609,0.00009641372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9043131,0.001344048,0.08148384,0.00003032633,0.000807577,0.00001932229,0.004875528,5.714757e-7,0.00003899456,0.00001911163,0.0001194493,0.006948168],"study_design_scores_gemma":[0.7753505,0.03288162,0.1905372,0.0001137045,0.0002863608,0.000005237129,0.0001547529,0.00001144397,0.0002060692,0.00001764458,0.0003345876,0.0001008675],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861064,0.00008037547,0.00002932383,0.001260302,0.0001222283,0.01065909,0.0001810557,0.00001831639,0.001542909],"genre_scores_gemma":[0.9924694,0.0001182288,0.0004842295,0.0002472261,0.0002929461,0.00598994,0.00001243314,0.00004739121,0.000338255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1289625,"threshold_uncertainty_score":0.4360817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0317431920055709,"score_gpt":0.327746268557953,"score_spread":0.2960030765523821,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}