{"id":"W2125665528","doi":"10.1200/jco.2015.62.1342","title":"Systemic Therapy for Stage IV Non–Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update","year":2015,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":851,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences","funders":"","keywords":"Medicine; Pemetrexed; Oncology; Gefitinib; Erlotinib; Internal medicine; Crizotinib; Docetaxel; Lung cancer; Carboplatin; Afatinib; Chemotherapy; Bevacizumab; Cancer; Epidermal growth factor receptor; Malignant pleural effusion; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.02242482,0.0003216325,0.00475002,0.00008456826,0.00007204941,0.00001343995,0.0004190161,0.0009345522,0.00007649123],"category_scores_gemma":[0.009520001,0.000219829,0.002280897,0.0002797329,0.0007520261,0.0002129917,0.0001019041,0.001866761,0.00001157162],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006707331,"about_ca_system_score_gemma":0.02385866,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003609189,"about_ca_topic_score_gemma":0.00008066391,"domain_scores_codex":[0.9857649,0.001726413,0.01086314,0.0005397198,0.000619793,0.0004860496],"domain_scores_gemma":[0.9696227,0.01120643,0.01275986,0.0005171089,0.004650167,0.001243687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.02370962,0.01099924,0.1616081,0.0001492852,0.005429714,0.0002817456,0.0004654544,0.0001855371,0.00005584982,0.00006066464,0.3294579,0.4675969],"study_design_scores_gemma":[0.04931903,0.04594608,0.01439176,0.0001514182,0.003924577,0.0002277811,0.002395834,0.002435231,0.00002214343,0.00004171534,0.8809467,0.0001977548],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8612616,0.008705594,0.01579753,0.09367865,0.01101939,0.002836435,0.0001559484,0.00004611282,0.006498754],"genre_scores_gemma":[0.4978086,0.0678947,0.3476489,0.06964326,0.01405097,0.0001420964,0.00006962448,0.0001400555,0.002601716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5514888,"threshold_uncertainty_score":0.9988232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.197713970446764,"score_gpt":0.6016853804165807,"score_spread":0.4039714099698167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}